Dave Umakant R, Williams Andreanna D, Wilson Jason A, Amin Zahir, Gilderdale David J, Larkman David J, Thursz Mark R, Taylor-Robinson Simon D, deSouza Nandita M
Departments of Gastroenterology and Anesthesia, Hammersmith Hospitals Trust, DuCane Rd, London W12 0HS, England.
Radiology. 2004 Jan;230(1):281-6. doi: 10.1148/radiol.2301021047. Epub 2003 Nov 26.
The authors defined esophageal anatomy and evaluated esophageal cancer staging in a pilot group by comparing endoscopic magnetic resonance (MR) imaging results with pathologic and endoscopic ultrasonographic (US) results when available. A porcine esophagus, one volunteer, and 23 patients suspected of having esophageal cancer were imaged at 0.5 T. MR imaging was successful in 21 patients. Eight of these patients underwent esophagectomy (one after chemotherapy, which invalidated comparison with MR imaging; another did not undergo lymphadenectomy) and one underwent laparoscopy and nodal staging only; eight underwent US. When verified with pathologic staging, endoscopic MR imaging was accurate in six of seven patients (T stage) and five of six patients (N stage; nodal areas too obscured by artifact for comparison in one case). MR imaging and US results concurred in seven of eight (T stage) and five of eight (N stage) patients. No complications were observed. Endoscopic MR imaging is safe and probably comparable to endoscopic US, but with a tendency to overstage the disease.
作者通过比较内镜磁共振（MR）成像结果与病理及内镜超声（US）结果（如有），对一组试验对象的食管解剖结构进行了定义，并评估了食管癌分期。对一头猪食管、一名志愿者以及23名疑似食管癌患者进行了0.5T的MR成像。21名患者的MR成像成功。其中8名患者接受了食管切除术（1名在化疗后进行，这使得与MR成像的比较无效；另1名未进行淋巴结清扫），1名仅接受了腹腔镜检查和淋巴结分期；8名接受了US检查。经病理分期验证，内镜MR成像在7名患者中的6名（T分期）以及6名患者中的5名（N分期；1例因伪影使淋巴结区域无法用于比较）中准确。MR成像和US结果在8名患者中的7名（T分期）以及8名患者中的5名（N分期）中一致。未观察到并发症。内镜MR成像安全，可能与内镜US相当，但有使疾病分期过高的倾向。
