Henriksen Trine F, Hölmich Lisbet R, Fryzek Jon P, Friis Søren, McLaughlin Joseph K, Høyer Annette Pernille, Kjøller Kim, Olsen Jørgen H
The Danish Registry for Plastic Surgery of the Breast, Strandboulevarden 49, DK-2100 Copenhagen, Denmark.
Ann Plast Surg. 2003 Dec;51(6):531-9. doi: 10.1097/01.sap.0000096446.44082.60.
The frequency and severity of local complications remain the primary safety issues with silicone breast implants. The Danish Registry for Plastic Surgery of the Breast (DPB), established in 1999, prospectively collects pre-, peri- and postoperative information regarding Danish women undergoing breast augmentation. Through DPB, we conducted a prospective follow-up study of short-term local complications among 1090 women who underwent cosmetic breast implantation from June 1999 through October 2002. Nineteen percent of women who underwent initial implantation developed at least 1 adverse effect. Forty percent of the adverse effects occurred within 3 months of implantation; 79%, within 6 months. Capsular contracture grade II-IV was observed among 4.1% of women in the 2-year follow-up period. Overall, 97 (29%) of the 344 adverse effects among 55 (6%) of the 971 women required surgical intervention. A higher incidence of adverse effects typically occurred after subsequent implantations. According to the DPB experience, we conclude that most short-term postoperative adverse effects following cosmetic implantation are clinically insignificant and do not require treatment and that short-term complications requiring adjuvant treatment are rare.
硅胶乳房植入物的局部并发症的发生率和严重程度仍然是主要的安全问题。丹麦乳房整形手术注册中心（DPB）成立于1999年，前瞻性地收集了丹麦接受隆胸手术女性的术前、术中和术后信息。通过DPB，我们对1999年6月至2002年10月期间接受美容性乳房植入的1090名女性的短期局部并发症进行了前瞻性随访研究。初次植入的女性中有19%至少出现了1种不良反应。40%的不良反应发生在植入后的3个月内；79%发生在6个月内。在2年的随访期内，4.1%的女性出现了II-IV级包膜挛缩。总体而言，971名女性中的55名（6%）出现的344种不良反应中有97种（29%）需要手术干预。再次植入后通常会出现更高的不良反应发生率。根据DPB的经验，我们得出结论，美容植入术后的大多数短期不良反应在临床上并不严重，不需要治疗，而需要辅助治疗的短期并发症很少见。
