Successful reduced-intensity HLA-haploidentical stem cell transplantation based on the concept of feto-maternal tolerance for an elderly patient with myelodysplastic syndrome.
作者信息
Obama K, Takemoto Y, Takatsuka Y, Utsunomiya A
出版信息
Bone Marrow Transplant. 2004 Jan;33(2):253. doi: 10.1038/sj.bmt.1704350.
PMID:14647244
Abstract
摘要
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Successful reduced-intensity HLA-haploidentical stem cell transplantation based on the concept of feto-maternal tolerance for an elderly patient with myelodysplastic syndrome.基于胎儿-母体耐受概念，成功为一名老年骨髓增生异常综合征患者进行了减低强度的HLA单倍型相合干细胞移植。
Bone Marrow Transplant. 2004 Jan;33(2):253. doi: 10.1038/sj.bmt.1704350.
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Successful use of haploidentical stem-cell transplantation with KIR mismatch as initial therapy for poor-risk myelodysplastic syndrome.成功使用单倍体相合干细胞移植联合杀伤细胞免疫球蛋白样受体（KIR）错配作为初治方案治疗高危骨髓增生异常综合征。
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Comparable non-relapse mortality and survival after HLA-identical sibling blood stem cell transplantation with reduced or conventional-intensity preparative regimens for high-risk myelodysplasia or acute myeloid leukemia in first remission.对于首次缓解期的高危骨髓增生异常综合征或急性髓系白血病患者，采用降低强度或传统强度预处理方案进行人类白细胞抗原（HLA）相合同胞血干细胞移植后的非复发死亡率和生存率比较。
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Survival after T cell-depleted haploidentical stem cell transplantation is improved using the mother as donor.使用母亲作为供体可提高T细胞去除的单倍体同基因干细胞移植后的生存率。
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