Hadler Maria Claret C M, Juliano Yara, Sigulem Dirce M
Nutrição, Universidade Federal de São Paulo, SP.
J Pediatr (Rio J). 2002 Jul-Aug;78(4):321-6.
To verify the prevalence of anemia, iron deficiency anemia and iron deficiency in infants, at a Public Health Unit in the city of Goiânia-Brazil; to analyze and to correlate the hematologic and biochemical variables.
A cross-sectional study was carried out. One hundred and ten full-term infants of the 120 mothers interviewed were included. The infants aged between six and twelve months and there were not twins. Socioeconomic and hematologic data was obtained. Venous blood was taken from fasting infants in order to carry out a complete hemogram through electronic cell counting, serum iron, serum ferritin and C-reactive protein, which were used in the evaluation of the etiology of iron deficiency in the anemic infants. Children with hemoglobin <11 g/dL were considered anemic.
The prevalence of anemia was 60.9%. In the diagnosis of the iron deficiency etiology in infants without an inflammation process, when considering the alteration of hemoglobin plus two more indices among mean corpuscular volume (MCV) or mean corpuscular hemoglobin (MCH) or serum ferritin or serum iron, the prevalence of the iron deficiency was 87%. Nevertheless, when red cell distribution width (RDW) was included in the indices, the prevalence was 97.8%. In the non-anemic infants, considering ferritin and RDW, the prevalence of iron deficiency observed was 28%. The best correlation among hematologic and biochemical variables were between hemoglobin and hematocrit (r=0.946), and MCH with MCV (r=0.950).
The main etiology in infants was iron deficiency anemia and its prevalence varied according to different parameters and criteria.
在巴西戈亚尼亚市的一个公共卫生单位，验证婴儿贫血、缺铁性贫血和铁缺乏的患病率；分析并关联血液学和生化变量。
开展了一项横断面研究。纳入了接受访谈的120名母亲所生的110名足月儿。这些婴儿年龄在6至12个月之间，且不是双胞胎。获取了社会经济和血液学数据。采集空腹婴儿的静脉血，以便通过电子细胞计数进行全血细胞计数、检测血清铁、血清铁蛋白和C反应蛋白，这些指标用于评估贫血婴儿缺铁的病因。血红蛋白<11 g/dL的儿童被视为贫血。
贫血患病率为60.9%。在无炎症过程的婴儿缺铁病因诊断中，若考虑血红蛋白变化加上平均红细胞体积（MCV）或平均红细胞血红蛋白含量（MCH）或血清铁蛋白或血清铁中的另外两项指标变化，铁缺乏患病率为87%。然而，若将红细胞分布宽度（RDW）纳入指标，患病率为97.8%。在非贫血婴儿中，考虑铁蛋白和RDW，观察到的铁缺乏患病率为28%。血液学和生化变量之间的最佳相关性存在于血红蛋白与血细胞比容之间（r = 0.946），以及MCH与MCV之间（r = 0.950）。
婴儿的主要病因是缺铁性贫血，其患病率根据不同参数和标准而有所不同。
