May Arne
Dept. of Neurology, University of Regensburg, 93053, Regensburg, Germany.
J Neurol. 2003 Nov;250(11):1273-8. doi: 10.1007/s00415-003-0241-y.
Primary short-lasting headaches broadly divide themselves into those associated with autonomic symptoms, so called trigemino-autonomic cephalgias (TACs), and those with little autonomic syndromes. The trigeminoautonomic cephalgias include cluster headache and paroxysmal hemicranias, in which head pain and cranial autonomic symptoms are prominent. The most striking feature of cluster headache is the circadian and circannual periodicity of the attacks. Inheritance may play a role in some families. The attacks are of extreme intensity, of short duration, occur unilaterally, and are accompanied by symptoms of autonomic dysfunction. Medical treatment includes both acute therapy aimed at aborting individual attacks and prophylactic therapy aimed at preventing recurrent attacks during the cluster period. Some types of trigemino-autonomic headaches, such as paroxysmal hemicrania and hemicrania continua have, unlike cluster headaches, a very robust response to indomethacin, leading to a consideration of indomethacin-sensitive headaches.
一类与自主神经症状相关,即所谓的三叉神经自主性头痛(TACs);另一类自主神经综合征较少。三叉神经自主性头痛包括丛集性头痛和发作性偏侧头痛,其中头痛和颅部自主神经症状较为突出。丛集性头痛最显著的特征是发作的昼夜节律和年节律。在某些家族中,遗传可能起作用。发作强度极大、持续时间短、单侧发生,并伴有自主神经功能障碍症状。药物治疗包括旨在终止单次发作的急性治疗和旨在预防丛集期复发发作的预防性治疗。与丛集性头痛不同,某些类型的三叉神经自主性头痛,如发作性偏侧头痛和持续性偏侧头痛,对吲哚美辛反应非常强烈,因此被视为对吲哚美辛敏感的头痛。