Rademaker Alfred W, Vonesh Edward F, Logemann Jeri A, Pauloski Barbara Roa, Liu Dachao, Lazarus Cathy L, Newman Lisa A, May Annette Hamner, MacCracken Ellen, Gaziano Joy, Stachowiak Linda
Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Suite 1102, 680 N. Lake Shore Drive, Chicago, IL 60611, USA.
Head Neck. 2003 Dec;25(12):1034-41. doi: 10.1002/hed.10317.
Head and neck cancer patients treated with chemoradiation have difficulty eating a normal diet. This study was designed to characterize eating ability over 12 months after chemoradiation treatment. Analyses take patient dropout into account.
Two hundred fifty-five patients with head and neck cancer treated with chemoradiation were followed for 12 months. Eating ability was analyzed using generalized linear model methods that accounted for non-ignorable dropout.
Eating ability was compromised immediately after treatment and improved over 12 months to near pretreatment levels. Ability to eat at most 50% of the diet orally did not return to baseline levels (p <.05). However, the percent of patients eating a normal diet did return to baseline levels. Accounting for dropout modified the results, but the pattern of significance was similar.
Treatment of head and neck cancer with chemoradiation has a significant effect on eating ability, which improves after 12 months after treatment.
Zotero 插件