Suzuki N, Takizawa H, Yamaguchi M, Matsuzaki G, Kiyosawa H, Dohi M, Ishii A, Suko M, Oka T, Ito K
Department of Medicine and Physical Therapy, University of Tokyo School of Medicine, Japan.
Nihon Kyobu Shikkan Gakkai Zasshi. 1992 Oct;30(10):1879-83.
Bronchoscopy was performed on a 68-year-old male patient with pulmonary tuberculosis, and revealed a yellow smooth polypoid tumor in the lumen of the left upper division bronchus. The histopathological diagnosis of the biopsy specimen was endobronchial lipoma. Since the patient did not have any symptoms due to the lipoma, we performed treatment for tuberculosis and continued careful observation of the tumor. During the subsequent 4 years, the patient developed no complications such as obstructive pneumonia, and the size of the tumor under bronchoscopic observation did not change. Endobronchial lipoma is a very rare benign tumor. Almost all reported cases have undergone operation or endoscopic surgery. This case is the first that was followed over 4 years without surgical procedure. The findings of follow-up bronchoscopic examination suggest that the growth rate of endobronchial lipoma is very slow. Furthermore, we reviewed 36 cases of endobronchial lipoma in the Japanese literature, including our case. Smoking seems to have a strong relation to the occurrence of the tumor. It is noteworthy that 6 cases had separate malignancies, but the direct relationship between endobronchial lipoma and such malignancies is unclear.
对一名68岁的男性肺结核患者进行了支气管镜检查，发现左肺上叶支气管腔内有一个黄色、表面光滑的息肉样肿瘤。活检标本的组织病理学诊断为支气管内脂肪瘤。由于患者没有因脂肪瘤出现任何症状，我们对其进行了抗结核治疗，并继续密切观察肿瘤情况。在随后的4年里，患者未出现诸如阻塞性肺炎等并发症，支气管镜观察下肿瘤大小也未改变。支气管内脂肪瘤是一种非常罕见的良性肿瘤。几乎所有已报道的病例都接受了手术或内镜手术。该病例是首例未经手术治疗且随访超过4年的病例。随访支气管镜检查结果表明，支气管内脂肪瘤的生长速度非常缓慢。此外，我们回顾了日本文献中包括本病例在内的36例支气管内脂肪瘤病例。吸烟似乎与该肿瘤的发生有密切关系。值得注意的是，有6例合并有其他恶性肿瘤，但支气管内脂肪瘤与这些恶性肿瘤之间的直接关系尚不清楚。
