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“DRIL”手术——一种治疗血液透析患者“窃血”综合征的被忽视的方法。

The "DRIL" procedure--a neglected way to treat the "steal" syndrome of the hemodialysed patient.

作者信息

Korzets Asher, Kantarovsky Alexander, Lehmann John, Sachs David, Gershkovitz Regina, Hasdan Galit, Vits Misha, Portnoy Isaak, Korzets Ze'ev

机构信息

Department of Nephrology, Hillel Yaffe Hospital, Hadera, Israel.

出版信息

Isr Med Assoc J. 2003 Nov;5(11):782-5.

Abstract

BACKGROUND

The ischemic "steal" syndrome complicates angio-access in a growing number of hemodialysed patients. Until now, operative attempts (fistula ligation or banding) to treat this problem have met with only limited success.

OBJECTIVE

To assess the results of DRIL (distal revascularization-interval ligation) procedure in treating the "steal" syndrome.

METHODS

A retrospective review (1996-2002) was conducted of all 11 patients who underwent the DRIL procedure in two tertiary care hemodialysis units.

RESULTS

Two patients were excluded because of inadequate medical documentation. All of the nine patients remaining suffered from overt atherosclerotic disease, six had diabetic nephropathy and four were smokers. The arteriovenous access, which led to the "steal" syndrome, was proximally located in all (antecubital in 8, thigh area in 1). "Steal" symptoms included hand pain, paraesthesia, neurologic deficits and gangrenous ulcers. DRIL was technically successful in all patients. There were no perioperative deaths. Immediate and complete relief of pain was achieved in eight of the nine patients. One patient with gangrene later required a transmetacarpal amputation. No patient required hand amputation. During follow-up (range 1-26 months) hemodialysis was continued uninterruptedly using the problematic AVA in all patients. Thrombosis occurred in the AVA in only two patients after the DRIL procedure at 9 and 24 months postoperatively, respectively. Three patient deaths were unrelated to the DRIL.

CONCLUSIONS

In selected patients the DRIL procedure is a safe and effective way to treat the "steal" syndrome. AVA patency is not compromised by this operation. Preoperative angiography, before and after manual compression of the AVA, is crucial for the proper selection of patients who will benefit most from the DRIL procedure.

摘要

背景

缺血性“窃血”综合征使越来越多接受血液透析的患者血管通路变得复杂。到目前为止,治疗这一问题的手术尝试(瘘管结扎或绑扎)仅取得了有限的成功。

目的

评估远端血管重建-节段结扎(DRIL)手术治疗“窃血”综合征的效果。

方法

对两家三级医疗血液透析单位中接受DRIL手术的11例患者进行回顾性研究(1996年至2002年)。

结果

2例患者因医疗记录不充分被排除。其余9例患者均患有明显的动脉粥样硬化疾病,6例患有糖尿病肾病,4例为吸烟者。导致“窃血”综合征的动静脉通路均位于近端(8例位于肘前,1例位于大腿区域)。“窃血”症状包括手部疼痛、感觉异常、神经功能缺损和坏疽性溃疡。DRIL手术在所有患者中技术上均获成功。无围手术期死亡病例。9例患者中有8例疼痛立即完全缓解。1例坏疽患者后来需要进行掌骨截肢。无患者需要手部截肢。在随访期间(1至26个月),所有患者均继续使用有问题的动静脉通路不间断地进行血液透析。DRIL手术后,仅2例患者的动静脉通路分别在术后9个月和24个月发生血栓形成。3例患者死亡与DRIL手术无关。

结论

对于选定的患者,DRIL手术是治疗“窃血”综合征的一种安全有效的方法。该手术不会损害动静脉通路的通畅性。术前对动静脉通路进行手动压迫前后的血管造影,对于正确选择将从DRIL手术中获益最大的患者至关重要。

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