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病毒感染的细胞免疫疗法。

The cellular immunotherapy of viral infection.

作者信息

Moss P A H, Cobbold M, Craddock C

机构信息

Cancer Research UK Institute for Cancer Studies, The University of Birmingham and University Hospitals NHS Trust, Birmingham, UK.

出版信息

Transfus Med. 2003 Dec;13(6):405-15. doi: 10.1111/j.1365-3148.2003.00468.x.

Abstract

Viral infections remain a major problem for the patient who has undergone a stem cell transplant and the introduction of increasingly more intensive SCT regimens suggests that this will remain a significant concern for the immediate future. Advances in basic immunology have led to an improved understanding of how immune responses control individual viral infections and this information is now being directly applied to patient care with encouraging results. The application of cellular immunotherapy to the immunocompromised patient is one of the most exciting areas of clinical medicine and offers the prospect of significant clinical impact.

摘要

对于接受干细胞移植的患者而言,病毒感染仍是一个重大问题。越来越强化的干细胞移植方案的引入表明,在可预见的未来,这仍将是一个重大关切。基础免疫学的进展使人们对免疫反应如何控制个体病毒感染有了更好的理解,并且这些信息目前正直接应用于患者护理,效果令人鼓舞。将细胞免疫疗法应用于免疫功能低下的患者是临床医学最令人兴奋的领域之一,有望产生重大的临床影响。

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