Management of cardiovascular risk factors in type 2 diabetic patients undergoing coronary angiography.

AIM

To investigate risk factor management in diabetic patients undergoing coronary angiography.

METHODS

Hemoglobin (Hgb) A1c, low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), triglycerides (TG), blood pressure (BP), and body mass index (BMI) were cardiovascular risk factors analyzed in 284 consecutive type 2 diabetic patients who underwent coronary angiography.

RESULTS

Coronary artery disease (CAD) was identified in 233 (82.0%) diabetic patients. The mean HgbA1c fraction for all patients at hospital admission was 9.7+/-1.4%. The mean concentration of LDL-C, HDL-C, and triglycerides was 2.82+/-0.9, 0.92+/-0.28, and 2.56+/-0.81 mmol/L, respectively. One hundred and twenty-two (43.0%) patients had LDL-C <2.6 mmol/L, 70 (24.7%) patients had a blood pressure of less than 130/85 mm Hg, and 158 (55.7%) had BMI <30 kg/m(2). Only 26 (9.1%) patients had optimal control of the above cardiac risk factors. The average LDL-C, triglycerides, and blood pressure in patients with severe coronary artery disease were higher than those in patients with moderate to mild coronary artery disease (p<0.01; unpaired t-test).

CONCLUSIONS

Cardiovascular risk factors were poorly controlled in type 2 diabetic patients. The average LDL-C, triglycerides, and blood pressure in patients with severe coronary artery disease were higher than those in patients with moderate to mild coronary artery disease.