Yeo Woon-Seok, Yousaf Muhammad N, Mrksich Milan
The University of Chicago, Department of Chemistry, Institute for Biophysical Dynamics, 5735 South Ellis Avenue, Chicago, Illinois 60637, USA.
J Am Chem Soc. 2003 Dec 10;125(49):14994-5. doi: 10.1021/ja038265b.
An electroactive substrate that combines dual dynamic properties is demonstrated. A monolayer is patterned to first release an immobilized ligand, and therefore adherent cells, on application of an electrical potential. Subsequently, electrical oxidation of the substrate results in immobilization of ligands, and migration of adherent cells.
展示了一种结合了双重动态特性的电活性基质。通过图案化单层结构,在施加电势时首先释放固定的配体,从而使贴壁细胞脱离。随后,基质的电氧化导致配体固定以及贴壁细胞迁移。