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新生儿高胆红素血症的管理:使用基准模型衡量绩效。

Management of hyperbilirubinemia in newborns: measuring performance by using a benchmarking model.

作者信息

Chou Shu-Chiung, Palmer R Heather, Ezhuthachan Sudhakar, Newman Christine, Pradell-Boyd Brenna, Maisels M Jeffrey, Testa Marcia A

机构信息

Center for Quality of Care Research and Education, Harvard School of Public Health, Boston, Massachusetts 02115, USA.

出版信息

Pediatrics. 2003 Dec;112(6 Pt 1):1264-73. doi: 10.1542/peds.112.6.1264.

Abstract

BACKGROUND

Accreditors hold hospitals accountable for harm from serious newborn hyperbilirubinemia, yet standards for evaluating performance in prevention are lacking.

OBJECTIVE

We confirmed prognostic variables for newborn hyperbilirubinemia and developed a benchmarking model for self-evaluation of hyperbilirubinemia management.

METHODS

We conducted a 3-year prospective cohort study in the Henry Ford Health System (HFHS) on 5507 healthy newborns of >or=35 weeks' gestational age. HFHS follows a rigorous protocol for hyperbilirubinemia management. Defining hyperbilirubinemia as age-specific levels of total serum bilirubin exceeding American Academy of Pediatrics criteria for considering phototherapy and severe hyperbilirubinemia as total serum bilirubin >or=20 mg/dL, we used logistic and Poisson regressions to determine predictors and estimate parameters for a benchmarking model. We compared incidence rates for severe hyperbilirubinemia from HFHS to aggregate data from 11 hospitals reported to have less rigorous management.

RESULTS

Newborns were 52.9% black, 14.4% white, 24.3% Latino, and 2.4% Asian; 30% were exclusively and 28% partially breastfed. Regression analyses revealed associations for hyperbilirubinemia and severe hyperbilirubinemia with black mothers (negative) and exclusive or partial breastfeeding and younger gestational age (positive). Male newborns and older mothers were also associated with severe hyperbilirubinemia. For all 5 variables, we found a lower risk for severe hyperbilirubinemia at HFHS than in the comparison hospital group. To compare hospitals, we developed a benchmarking model for incidence of hyperbilirubinemia adjusting for race, feeding method, and gestational age.

CONCLUSIONS

Hospitals with access to newborns' inpatient and postdischarge data can use our benchmarking model to compare their management of hyperbilirubinemia with a reference population that received rigorous care.

摘要

背景

评审机构要求医院对严重新生儿高胆红素血症所致伤害负责,但缺乏评估预防工作表现的标准。

目的

我们确定了新生儿高胆红素血症的预后变量,并开发了一个用于高胆红素血症管理自我评估的基准模型。

方法

我们在亨利·福特医疗系统(HFHS)对5507名胎龄≥35周的健康新生儿进行了为期3年的前瞻性队列研究。HFHS遵循严格的高胆红素血症管理方案。将高胆红素血症定义为血清总胆红素水平超过美国儿科学会光疗标准,将严重高胆红素血症定义为血清总胆红素≥20mg/dL,我们使用逻辑回归和泊松回归来确定预测因素并估计基准模型的参数。我们将HFHS的严重高胆红素血症发病率与11家报告管理较宽松的医院的汇总数据进行了比较。

结果

新生儿中52.9%为黑人,14.4%为白人,24.3%为拉丁裔,2.4%为亚洲人;30%为纯母乳喂养,28%为部分母乳喂养。回归分析显示,高胆红素血症和严重高胆红素血症与黑人母亲(呈负相关)、纯母乳喂养或部分母乳喂养以及较小胎龄(呈正相关)有关。男婴和年龄较大的母亲也与严重高胆红素血症有关。对于所有这5个变量,我们发现HFHS的严重高胆红素血症风险低于比较医院组。为了比较不同医院,我们开发了一个针对高胆红素血症发病率的基准模型,该模型根据种族、喂养方式和胎龄进行了调整。

结论

能够获取新生儿住院和出院后数据的医院可以使用我们的基准模型,将其高胆红素血症管理情况与接受严格治疗的参考人群进行比较。

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