距下关节原发性滑膜软骨瘤病累及两兄弟。

Primary synovial chondromatosis of the subtalar joint affecting two brothers.

作者信息

Hocking Richard, Negrine John

机构信息

Orthopaedic Registrar Westmead Hospital, New South Wales, Australia.

出版信息

Foot Ankle Int. 2003 Nov;24(11):865-7. doi: 10.1177/107110070302401111.

DOI:10.1177/107110070302401111

PMID:14655893

Abstract

Primary synovial chondromatosis is a rare benign condition characterized by the formation of multiple cartilaginous nodules in the synovium of joints and on occasions tendon sheaths or bursae. A case of primary synovial chondromatosis affecting the subtalar joint is reported. The patient's brother developed the same condition affecting the same joint 2 years later. The proposed etiologies are discussed including the presence of the proto-oncogene C-erb B-2.

摘要

原发性滑膜软骨瘤病是一种罕见的良性疾病，其特征是在关节滑膜以及偶尔在腱鞘或滑囊中形成多个软骨结节。本文报道了一例累及距下关节的原发性滑膜软骨瘤病病例。该患者的兄弟在两年后也出现了同一关节的相同病症。文中讨论了包括原癌基因C-erb B-2存在在内的推测病因。