N-tritylprolinal: an efficient building block for the stereoselective synthesis of proline-derived amino alcohols.
作者信息
Bejjani Joseph, Chemla Fabrice, Audouin Max
机构信息
Laboratoire de Chimie Organique, UMR 7611, Université Pierre et Marie Curie, Tour 44 - 45 2ème étage, 4 Place Jussieu, 75252 Paris Cedex 05, France.
出版信息
J Org Chem. 2003 Dec 12;68(25):9747-52. doi: 10.1021/jo034976g.
PMID:14656102
Abstract
N-Tritylprolinal (prepared in four steps from l-proline) shows a very high Felkin diastereoselectivity in its reaction with various nucleophiles, leading to a straightforward and highly stereoselective access to syn-proline-derived amino alcohols.
摘要
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