Yanardag H, Pamuk O N, Karayel T
Department of Lung Diseases, Cerrahpaşa Medical Faculty, University of Istanbul, Istanbul.
Intern Med J. 2003 Nov;33(11):535-7. doi: 10.1046/j.1445-5994.2003.00466.x.
In the 36-year period between 1966 and 2002, 514 patients were diagnosed with sarcoidosis at Cerrahpaşa Medical Faculty, Istanbul, Turkey, and of these 98 (19.1%) had Löfgren syndrome. The frequency of female patients with Löfgren was higher than the frequency among other sarcoidosis patients (female:male ratio 4.8 vs. 1.64; P < 0.001). Erythema nodosum was diagnosed in 72.4% of the subjects and arthritis or arthralgia was diagnosed in 51%. Erythema nodosum and arthritis or arthralgia were more frequent in Löfgren; however, pulmonary parenchymal involvement was more frequent in other sarcoidosis patients (all P-values < 0.001).
在1966年至2002年的36年期间,土耳其伊斯坦布尔的切拉帕夏医学院诊断出514例结节病患者,其中98例(19.1%)患有 Löfgren 综合征。患有Löfgren综合征的女性患者比例高于其他结节病患者(女性与男性比例为4.8比1.64;P < 0.001)。72.4%的患者被诊断为结节性红斑,51%的患者被诊断为关节炎或关节痛。结节性红斑和关节炎或关节痛在Löfgren综合征患者中更为常见;然而,肺部实质受累在其他结节病患者中更为常见(所有P值< 0.001)。