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[儿童青霉素过敏]

[Penicillin allergy in children].

作者信息

Abinun M

机构信息

Mother and Child Health Institute of Serbia, Belgrade.

出版信息

Srp Arh Celok Lek. 1992 May-Jun;120(5-6):206-8.

PMID:1465679
Abstract

Penicillin allergy in children is overdiagnosed and paediatricians, fearing the possibility of fatal anaphylaxis, seldom question a report that a child is allergic to penicillin. Laboratory tests to predict whether a patient will react to penicillin are unhelpful in routine clinical practice and skin tests themselves carry a significant risk of anaphylaxis and even death. A few simple inquiries can often exclude the diagnosis. However, a history of penicillin therapy associated with an immediate reaction suggests penicillin allergy.

摘要

儿童青霉素过敏被过度诊断,儿科医生因担心致命性过敏反应的可能性,很少质疑儿童对青霉素过敏的报告。在常规临床实践中,预测患者是否会对青霉素产生反应的实验室检测并无帮助,而皮肤试验本身就有发生过敏反应甚至死亡的重大风险。一些简单询问往往可以排除该诊断。然而,与即刻反应相关的青霉素治疗史提示青霉素过敏。

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