COX-3——人类潜在的疼痛靶点？ - Suppr

COX-3--a virtual pain target in humans?

作者信息

Schwab Jan M, Beiter Thomas, Linder Juergen U, Laufer Stefan, Schulz Joachim E, Meyermann Richard, Schluesener Hermann J

机构信息

Institute of Brain Research, University of Tuebingen, Germany.

出版信息

FASEB J. 2003 Dec;17(15):2174-5. doi: 10.1096/fj.03-0595lte.

DOI:10.1096/fj.03-0595lte

PMID:14656977

Abstract

摘要

相似文献

COX-3--a virtual pain target in humans?

FASEB J. 2003 Dec;17(15):2174-5. doi: 10.1096/fj.03-0595lte.

Cyclooxygenase-3 (COX-3): filling in the gaps toward a COX continuum?

Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13371-3. doi: 10.1073/pnas.222543099. Epub 2002 Oct 8.

COX in a crystal ball: current status and future promise of prostaglandin research.

J Clin Invest. 2001 Jun;107(11):1335-7. doi: 10.1172/JCI13037.

Cloning, expression, and selective inhibition of canine cyclooxygenase-1 and cyclooxygenase-2.

Vet Ther. 2002 Fall;3(3):270-80.

Independent prostanoid biosynthetic systems associated with prostaglandin endoperoxide synthases-1 and -2.

Thromb Haemost. 1997 Jul;78(1):627-30.

[Progress in the study of cyclooxygenase].

Sheng Li Ke Xue Jin Zhan. 2004 Jan;35(1):81-3.

[Cyclooxygenases in the spinal cord and the relationship with pain].

Sheng Li Ke Xue Jin Zhan. 2003 Oct;34(4):359-60.

Size- and invasion-dependent increase in cyclooxygenase 2 levels in human colorectal carcinomas.

Cancer Res. 1998 Nov 1;58(21):4823-6.

Genetic variation in cyclooxygenase 1: effects on response to aspirin.

Clin Pharmacol Ther. 2003 Jan;73(1):122-30. doi: 10.1067/mcp.2003.1.

Transcriptional regulation of cyclo-oxygenase expression: three pillars of control.

Int J Immunopathol Pharmacol. 2003 May-Aug;16(2 Suppl):59-67.

引用本文的文献

An Updated Review on the Metabolite (AM404)-Mediated Central Mechanism of Action of Paracetamol (Acetaminophen): Experimental Evidence and Potential Clinical Impact.

J Pain Res. 2023 Mar 29;16:1081-1094. doi: 10.2147/JPR.S393809. eCollection 2023.

Paracetamol (acetaminophen): A familiar drug with an unexplained mechanism of action.

Temperature (Austin). 2021 Mar 16;8(4):351-371. doi: 10.1080/23328940.2021.1886392. eCollection 2021.

Arachidonic Acid Metabolism and Kidney Inflammation.

Int J Mol Sci. 2019 Jul 27;20(15):3683. doi: 10.3390/ijms20153683.

The modern pharmacology of paracetamol: therapeutic actions, mechanism of action, metabolism, toxicity and recent pharmacological findings.

Inflammopharmacology. 2013 Jun;21(3):201-32. doi: 10.1007/s10787-013-0172-x. Epub 2013 May 30.

Effects of prostaglandins and COX-inhibiting drugs on skeletal muscle adaptations to exercise.

J Appl Physiol (1985). 2013 Sep;115(6):909-19. doi: 10.1152/japplphysiol.00061.2013. Epub 2013 Mar 28.

Inhibition of COX-2 expression by topical diclofenac enhanced radiation sensitivity via enhancement of TRAIL in human prostate adenocarcinoma xenograft model.

BMC Urol. 2013 Jan 5;13:1. doi: 10.1186/1471-2490-13-1.

[Pain therapy with antipyretic analgesics].

Orthopade. 2007 Jan;36(1):23-31. doi: 10.1007/s00132-006-1024-9.

The role of cyclooxygenase in gastric mucosal protection.

Dig Dis Sci. 2005 Oct;50 Suppl 1:S16-23. doi: 10.1007/s10620-005-2802-7.

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COX-3--a virtual pain target in humans?

作者信息

Schwab Jan M, Beiter Thomas, Linder Juergen U, Laufer Stefan, Schulz Joachim E, Meyermann Richard, Schluesener Hermann J

机构信息

Institute of Brain Research, University of Tuebingen, Germany.

出版信息

FASEB J. 2003 Dec;17(15):2174-5. doi: 10.1096/fj.03-0595lte.

DOI:10.1096/fj.03-0595lte

PMID:14656977

Abstract

摘要

相似文献

COX-3--a virtual pain target in humans?

FASEB J. 2003 Dec;17(15):2174-5. doi: 10.1096/fj.03-0595lte.

Cyclooxygenase-3 (COX-3): filling in the gaps toward a COX continuum?

Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13371-3. doi: 10.1073/pnas.222543099. Epub 2002 Oct 8.

COX in a crystal ball: current status and future promise of prostaglandin research.

J Clin Invest. 2001 Jun;107(11):1335-7. doi: 10.1172/JCI13037.

Cloning, expression, and selective inhibition of canine cyclooxygenase-1 and cyclooxygenase-2.

Vet Ther. 2002 Fall;3(3):270-80.

Independent prostanoid biosynthetic systems associated with prostaglandin endoperoxide synthases-1 and -2.

Thromb Haemost. 1997 Jul;78(1):627-30.

[Progress in the study of cyclooxygenase].

Sheng Li Ke Xue Jin Zhan. 2004 Jan;35(1):81-3.

[Cyclooxygenases in the spinal cord and the relationship with pain].

Sheng Li Ke Xue Jin Zhan. 2003 Oct;34(4):359-60.

Size- and invasion-dependent increase in cyclooxygenase 2 levels in human colorectal carcinomas.

Cancer Res. 1998 Nov 1;58(21):4823-6.

Genetic variation in cyclooxygenase 1: effects on response to aspirin.

Clin Pharmacol Ther. 2003 Jan;73(1):122-30. doi: 10.1067/mcp.2003.1.

Transcriptional regulation of cyclo-oxygenase expression: three pillars of control.

Int J Immunopathol Pharmacol. 2003 May-Aug;16(2 Suppl):59-67.

引用本文的文献

An Updated Review on the Metabolite (AM404)-Mediated Central Mechanism of Action of Paracetamol (Acetaminophen): Experimental Evidence and Potential Clinical Impact.

J Pain Res. 2023 Mar 29;16:1081-1094. doi: 10.2147/JPR.S393809. eCollection 2023.

Paracetamol (acetaminophen): A familiar drug with an unexplained mechanism of action.

Temperature (Austin). 2021 Mar 16;8(4):351-371. doi: 10.1080/23328940.2021.1886392. eCollection 2021.

Arachidonic Acid Metabolism and Kidney Inflammation.

Int J Mol Sci. 2019 Jul 27;20(15):3683. doi: 10.3390/ijms20153683.

The modern pharmacology of paracetamol: therapeutic actions, mechanism of action, metabolism, toxicity and recent pharmacological findings.

Inflammopharmacology. 2013 Jun;21(3):201-32. doi: 10.1007/s10787-013-0172-x. Epub 2013 May 30.

Effects of prostaglandins and COX-inhibiting drugs on skeletal muscle adaptations to exercise.

J Appl Physiol (1985). 2013 Sep;115(6):909-19. doi: 10.1152/japplphysiol.00061.2013. Epub 2013 Mar 28.

Inhibition of COX-2 expression by topical diclofenac enhanced radiation sensitivity via enhancement of TRAIL in human prostate adenocarcinoma xenograft model.

BMC Urol. 2013 Jan 5;13:1. doi: 10.1186/1471-2490-13-1.

[Pain therapy with antipyretic analgesics].

Orthopade. 2007 Jan;36(1):23-31. doi: 10.1007/s00132-006-1024-9.

The role of cyclooxygenase in gastric mucosal protection.

Dig Dis Sci. 2005 Oct;50 Suppl 1:S16-23. doi: 10.1007/s10620-005-2802-7.

COX-3--a virtual pain target in humans?

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COX-3--a virtual pain target in humans?

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