Teruel J L, Fernández Lucas M, Arambarri M, Merino J L, Echarri R, Alarcón C, Marcén R, Rivera M, Ortuño J
Servicio de Nefrología Hospital Ramón y Cajal Ctra. de Colmenar, km. 9,100, 28034 Madrid.
Nefrologia. 2003 Sep-Oct;23(5):444-50.
The Diascan equipment (Hospal) measures ionic dialysane which it derives the K and the Kt. If we divide the Kt obtained with Diascan between the Kt/V obtained by a simplified formula, it result a value of V for every patient. Entering this V in the Diascan software we can obtain a Kt/V (Diascan Kt/V), similar in theory to the simplified Kt/V. In the year 2002 we have controlled the delivered dialysis in our unit with the Diascan Kt/V. The aim of the present study was to study the agreement between de Diascan Kt/V and the Lowrie Kt/V. During the year 2002, 63 patients have been dialyzed in monitors with Diascan equipment. We calculated the V of each patient by dividing the Kt Diascan between the Lowrie Kt/V in the same dialysis session. The mea of the two consecutive measurements was considered the V value. Throughout the year 2002, 7 agreement studies were realized. The inter-method variability was assessed by the relative difference (absolute difference Diascan Kt/V-Lowrie Kt/V, divided by the average of both tests). A good agreement was considered when the relative difference was equal or lower than 10%. In the 7 agreement studies realized, the mean of the relative difference oscilled between 5.2 and 6.6%, and the percentage of patients with a relative difference equal or lower than 10% oscilled between 83 and 91%. During a month, the Diascan Kt/V was controlled in all dialysis sessions in 41 patients (554 sessions in total). Failure in the lecture of Kt/V Diascan was observed in 41 sessions (7%). A Diascan Kt/V greater than 1 (the minimum delivered dialysis considered in our unit) was obtained in 93% of the valid sessions. 38 of 41 patients had a mean monthly Diascan Kt/V greater than 1. The coefficient of variability of any patient oscilled between 2.1 and 12.4% (mean 5.1%). Diascan Kt/V is good procedure for the monitoring the delivered dialysis without blood sampling or any additional costs.
Diascan设备（Hospal公司）可测量离子透析率，并由此得出K值和Kt值。若用Diascan测得的Kt值除以用简化公式得出的Kt/V值，就能得到每位患者的V值。将此V值输入Diascan软件，我们就能得到一个理论上与简化Kt/V值相似的Diascan Kt/V值。2002年，我们用Diascan Kt/V对本单位的透析治疗情况进行了监测。本研究的目的是探究Diascan Kt/V与Lowrie Kt/V之间的一致性。2002年期间，63例患者使用Diascan设备进行了透析监测。我们通过在同一透析疗程中用Diascan测得的Kt值除以Lowrie Kt/V值来计算每位患者的V值。取连续两次测量的平均值作为V值。在2002年全年，共进行了7次一致性研究。通过相对差异（Diascan Kt/V - Lowrie Kt/V的绝对差值除以两次检测结果的平均值）来评估方法间的变异性。当相对差异等于或低于10%时，认为一致性良好。在进行的7次一致性研究中，相对差异的平均值在5.2%至6.6%之间波动，相对差异等于或低于10%的患者比例在83%至91%之间波动。在一个月内，对41例患者（共554次透析疗程）的所有透析疗程进行了Diascan Kt/V监测。在41次疗程中观察到Diascan Kt/V读数失败（占7%）。在93%的有效疗程中获得了大于1（本单位认为的最低透析剂量）的Diascan Kt/V值。41例患者中有38例的月平均Diascan Kt/V大于1。任何一位患者的变异系数在2.1%至12.4%之间波动（平均为5.1%）。Diascan Kt/V是一种无需采血或额外费用就能监测透析剂量的良好方法。
