Kato Haruhisa, Iijima Mutsumi, Hiroi Atuko, Kubo Masashi, Uchigata Masanobu
Department of Neurology, Showa General Hospital.
Rinsho Shinkeigaku. 2003 Aug;43(8):487-90.
We report a 63-year-old right-handed man who presented an alien hand syndrome (AHS). He complained of clumsiness of his left hand and admitted to our hospital. On the first examination, he presented left homonymous hemianopia, left spatial neglect and left limb ataxia, but neither paralysis nor sensory impairment. A few days after, he complained that his left hand was controlled by someone else, and we considered this phenomenon as AHS. At that time, he lost sensation of almost all modalities including deep sensation on his left upper and lower limb. Magnetic resonance image examination was performed, and it showed acute cerebral infarction at right posterior cerebral artery territory including right thalamus (ventral posterior lateral nucleus). Generally, AHS is caused by left mediofrontal and callosal lesion (frontal type AHS), or by callosal with bilateral frontal or without frontal lesion (callosal type AHS). However, some cases were reported that they presented AHS after damage of the basal ganglia, right thalamus, right occipital or inferior parietal lobe. Some authors described this phenomenon as "sensory" or "posterior" type AHS. In such cases, included our case, we speculate that sensory impairment causes AHS. Especially in our case, AHS might be caused by not only the sensory impairment but also by left homonymous hemianopia and left spatial neglect. So, because of these symptoms, our patient could not recognize the motion of the left hand, and presented AHS. We think that this "sensory" or "posterior" type AHS should be distinguished from frontal and callosal type AHS.
我们报告了一名63岁的右利手男性,他患有异己手综合征(AHS)。他主诉左手笨拙并入住我院。首次检查时,他表现为左侧同向性偏盲、左侧空间忽视和左侧肢体共济失调,但无瘫痪或感觉障碍。几天后,他抱怨自己的左手不受自己控制,我们将这种现象视为异己手综合征。当时,他左侧上下肢几乎所有感觉模态包括深感觉均丧失。进行了磁共振成像检查,结果显示右侧大脑后动脉供血区包括右侧丘脑(腹后外侧核)急性脑梗死。一般来说,异己手综合征由左侧额中回和胼胝体病变(额叶型异己手综合征)引起,或由胼胝体合并双侧额叶病变或无额叶病变引起(胼胝体型异己手综合征)。然而,有报道称一些病例在基底节、右侧丘脑、右侧枕叶或顶下小叶受损后出现异己手综合征。一些作者将这种现象描述为“感觉性”或“后部型”异己手综合征。在包括我们病例在内的此类病例中,我们推测感觉障碍导致了异己手综合征。特别是在我们的病例中,异己手综合征可能不仅由感觉障碍引起,还由左侧同向性偏盲和左侧空间忽视导致。所以,由于这些症状,我们的患者无法感知左手的运动,从而出现了异己手综合征。我们认为这种“感觉性”或“后部型”异己手综合征应与额叶型和胼胝体型异己手综合征相区分。