一种用于关联在重水（D₂O）和水（H₂O）中测定的pKa值的公式。

A formula for correlating pKa values determined in D2O and H2O.

作者信息

Krezel Artur, Bal Wojciech

机构信息

Faculty of Chemistry, University of Wroclaw, Joliot-Curie 14, 50-383 Wroclaw, Poland.

出版信息

J Inorg Biochem. 2004 Jan;98(1):161-6. doi: 10.1016/j.jinorgbio.2003.10.001.

DOI:10.1016/j.jinorgbio.2003.10.001

PMID:14659645

Abstract

A linear correlation between pH-meter readings in equivalent D2O and H2O solutions, determined experimentally, leads to a novel equation, which allows for a direct recalculation of pKa values measured in D2O into a H2O equivalent: pKH=0.929pKH*+0.42. The comparison of this equation with the previously used approach is discussed.

摘要

通过实验测定，在等效重水（D₂O）和水（H₂O）溶液中pH计读数之间的线性相关性，得出了一个新方程，该方程允许将在重水中测得的pKa值直接重新计算为水等效值：pKH = 0.929pKH* + 0.42。讨论了该方程与先前使用方法的比较。