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妇女健康倡议对女性停止绝经后激素治疗决策的影响。

Effect of the Women's Health Initiative on women's decisions to discontinue postmenopausal hormone therapy.

作者信息

Ettinger Bruce, Grady Deborah, Tosteson Anna N A, Pressman Alice, Macer Judith L

机构信息

Division of Research, Kaiser Permanente Northern California, Oakland, Oakland, California 94611-5714, USA.

出版信息

Obstet Gynecol. 2003 Dec;102(6):1225-32. doi: 10.1016/j.obstetgynecol.2003.08.007.

Abstract

OBJECTIVE

To examine whether women who were using postmenopausal hormone therapy (HT) before publication of Women's Health Initiative findings about risks associated with HT had been informed about the findings once published; and to estimate how knowledge of these findings was associated with their decision to discontinue HT.

METHODS

We performed a telephone survey of 670 female members of a large health maintenance organization, aged 50-69 yr, who had regularly used HT from July 1, 2001, through June 30, 2002.

RESULTS

Most women (93%) reported hearing about the new findings; however, only 57% considered the quality of this information to be good, regardless of its source: mass media (21%), the health plan (32%), or a health care practitioner (34%). Women's knowledge of Women's Health Initiative findings was generally poor; 64% did not know what the findings were, 7% were unsure of their knowledge, 6% had incorrect knowledge, and 23% had correct knowledge of Women's Health Initiative findings. On a simple, five-question, true-or-false quiz about HT risks, 30% of respondents answered four to five questions correctly. Although not well informed, 56% reported attempting to discontinue HT in the 6 to 8 months after July 2002. Our multivariable model included five statistically significant predictors of attempting to stop HT: having been sent a letter about Women's Health Initiative findings (odds ratio [OR] 2.7; 95% confidence interval [CI] 1.8, 3.9), reporting good-quality information from media (OR 2.1; 95% CI 1.3, 3.3), having started HT for health promotion (OR 2.0; 95% CI 1.2, 3.3), using a lower-than-standard dosage of estrogen (OR 1.9; 95% CI 1.1, 3.1), and correctly answering four or more items on the HT quiz (OR 1.9; 95% CI 1.2, 2.8).

CONCLUSION

During the 6-8 months after publication of Women's Health Initiative trial findings, most regular postmenopausal HT users tried to stop using HT, despite not being well informed about the Women's Health Initiative findings.

摘要

目的

探讨在《妇女健康倡议》发布关于绝经后激素治疗(HT)相关风险的研究结果之前正在使用HT的女性,在结果发布后是否被告知这些结果;并评估对这些结果的了解程度与她们决定停用HT之间的关联。

方法

我们对一家大型健康维护组织的670名年龄在50 - 69岁之间的女性成员进行了电话调查,这些女性在2001年7月1日至2002年6月30日期间定期使用HT。

结果

大多数女性(93%)报告听说了新的研究结果;然而,无论信息来源如何(大众媒体占21%、健康计划占32%、医疗保健从业者占34%),只有57%的女性认为这些信息质量良好。女性对《妇女健康倡议》研究结果的了解普遍较差;64%的女性不知道研究结果是什么,7%不确定自己的了解情况,6%有错误的了解,23%对《妇女健康倡议》研究结果有正确的了解。在一个关于HT风险的简单的五道是非题测验中,30%的受访者答对了四至五道题。尽管了解不足,但56%的女性报告在2002年7月后的6至8个月内试图停用HT。我们的多变量模型包括五个试图停用HT的具有统计学意义的预测因素:收到关于《妇女健康倡议》研究结果的信件(优势比[OR] 2.7;9

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