Inoue H, Iwabuchi K, Kuwao S, Kasai K, Furuhata M, Kameya T
Department of Pathology, Kitasato University, School of Medicine, Kanagawa, Japan.
Acta Pathol Jpn. 1992 Oct;42(10):760-5. doi: 10.1111/j.1440-1827.1992.tb03228.x.
A case of inflammatory pseudosarcoma of the urinary bladder in a 35-year-old Japanese male is presented. This benign lesion can easily be mistaken for spindle cell sarcoma since it consists of rhabdomyoblast-like elongated strap cells showing infiltrative growth, and whether it is benign or malignant is difficult to determine by microscopic examination. In this case, spindle cell proliferation extended among bundles of the superficial muscle layer. However, no abnormal mitoses, severe nuclear atypia or cellular pleomorphism could be seen, thus indicating inflammatory pseudosarcoma. Although the lesion was not completely resected, no recurrent disease has been clinically observed for two years following transurethral resection. Urologists and surgical pathologists must be able to detect this lesion in order to avoid unnecessary surgical procedures.
本文报告了一例35岁日本男性膀胱炎性假肉瘤病例。这种良性病变很容易被误诊为梭形细胞肉瘤，因为它由横纹肌母细胞样的细长带状细胞组成，呈浸润性生长，通过显微镜检查很难确定其是良性还是恶性。在该病例中，梭形细胞增生扩展至浅表肌层束之间。然而，未见异常有丝分裂、严重核异型性或细胞多形性，因此诊断为炎性假肉瘤。尽管病变未完全切除，但经尿道切除术后两年临床未观察到复发病例。泌尿外科医生和外科病理学家必须能够识别这种病变，以避免不必要的手术。
