Braun P
Herzzentrum Kaiser-Wilhelm-Krankenhaus, Medizinische Klinik III Abt. Kardiologie, TX-Ambulanz, Gerrickstrasse 21, 47137 Duisburg, Germany.
Z Kardiol. 2003;92(Suppl 3):III48-52. doi: 10.1007/s00392-003-1305-9.
Long-run development of heart transplanted patients is predominantly determined by the occurrence of graft vasculopathy. Due to the commonly diffuse and concentrical appearance of plaque in the coronary vessels, the disease defies, at least in the early stage, the conventionally used angiographic diagnostic procedures with radiocontrast agents. With the possibility to differentiate not only the lumen but also structures of the vessel walls and different tissue types, intracoronary ultrasound (IVUS) of coronary vessels yields entirely new insights in the development, the course and the prognostic importance of graft vasculopathy. Besides the extended scientific application in order to investigate the pathophysiology of graft vasculopathy and the assessment of therapeutic strategies, regular follow-ups with IVUS are nowadays used in many centers in routine care after heart transplant.
心脏移植患者的长期发展主要由移植血管病变的发生所决定。由于冠状动脉中斑块通常呈弥漫性和同心性外观，该疾病至少在早期阶段难以通过传统的使用放射性造影剂的血管造影诊断程序进行检测。冠状动脉内超声（IVUS）不仅能够区分管腔，还能区分血管壁结构和不同组织类型，从而为移植血管病变的发展、进程及预后重要性提供全新的见解。除了在研究移植血管病变的病理生理学和评估治疗策略方面的广泛科学应用外，如今许多中心在心脏移植后的常规护理中也会定期使用IVUS进行随访。
