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糖尿病对当前心力衰竭住院管理的影响。来自TEMISTOCLE研究。

Impact of diabetes on the current in-hospital management of heart failure. From the TEMISTOCLE study.

作者信息

Opasich Cristina, Cafiero Massimo, Scherillo Marino, De Feo Stefania, Caputo Francesco, Gonzini Lucio, Lavecchia Rinaldo, Loru Franco, Maggioni Aldo P

机构信息

Department of Cardiology, Salvatore Maugeri Foundation, Pavia, Italy.

出版信息

Ital Heart J. 2003 Oct;4(10):685-94.

Abstract

BACKGROUND

Little is known about the clinical profile, use of resources, management and outcome of a large population of diabetic patients with heart failure managed in a community setting.

METHODS

A prospective cross-sectional survey in the setting of acute hospital admissions for heart failure to 167 cardiology and 250 internal medicine departments between February 14 and 25, 2000.

RESULTS

Among the 2127 consecutively admitted patients, 603 (28.4%) had a history of diabetes; they were significantly younger, had a lower rate of atrial fibrillation, and a more frequent ischemic etiology than non-diabetics. Just as non-diabetic patients, diabetics underwent invasive and non-invasive procedures in a low percentage of cases, even though slightly more frequently when managed by cardiologists. Diabetic patients were less frequently prescribed amiodarone and anticoagulants, and more frequently prescribed nitrates and antiplatelets. The all-cause in-hospital mortality rate was similar among diabetics and non-diabetics (5.3 vs 5.7%, p = NS). Adjusted analysis confirmed that diabetes is not independently associated with a worse outcome.

CONCLUSIONS

In a community setting diabetes per se has only a slight impact on the management and outcome of patients with heart failure.

摘要

背景

对于在社区环境中管理的大量糖尿病合并心力衰竭患者的临床特征、资源利用、管理及结局,人们了解甚少。

方法

2000年2月14日至25日期间,对167个心脏病科和250个内科收治的因心力衰竭急性住院的患者进行前瞻性横断面调查。

结果

在2127例连续入院的患者中,603例(28.4%)有糖尿病史;与非糖尿病患者相比,他们明显更年轻,房颤发生率更低,缺血性病因更常见。与非糖尿病患者一样,糖尿病患者接受侵入性和非侵入性检查的比例较低,尽管由心脏病专家管理时频率略高。糖尿病患者使用胺碘酮和抗凝剂的频率较低,使用硝酸盐和抗血小板药物的频率较高。糖尿病患者和非糖尿病患者的全因住院死亡率相似(5.3%对5.7%,p=无显著性差异)。校正分析证实糖尿病并非独立与更差的结局相关。

结论

在社区环境中,糖尿病本身对心力衰竭患者的管理和结局仅有轻微影响。

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