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荟萃分析中二分结局的效应量指标。

Effect-size indices for dichotomized outcomes in meta-analysis.

作者信息

Sánchez-Meca Julio, Marín-Martínez Fulgencio, Chacón-Moscoso Salvador

机构信息

U Murcia, Dept of Basic Psychology & Methodology, Faculty of Psychology, Murcia, Spain.

出版信息

Psychol Methods. 2003 Dec;8(4):448-67. doi: 10.1037/1082-989X.8.4.448.

DOI:10.1037/1082-989X.8.4.448
PMID:14664682
Abstract

It is very common to find meta-analyses in which some of the studies compare 2 groups on continuous dependent variables and others compare groups on dichotomized variables. Integrating all of them in a meta-analysis requires an effect-size index in the same metric that can be applied to both types of outcomes. In this article, the performance in terms of bias and sampling variance of 7 different effect-size indices for estimating the population standardized mean difference from a 2 x 2 table is examined by Monte Carlo simulation, assuming normal and nonnormal distributions. The results show good performance for 2 indices, one based on the probit transformation and the other based on the logistic distribution.

摘要

在荟萃分析中,经常会发现一些研究在连续因变量上比较两组,而另一些研究则在二分变量上比较组间差异。要将所有这些研究纳入荟萃分析,就需要一个统一的效应量指标,该指标应能适用于这两种类型的结果。本文通过蒙特卡洛模拟,在假设正态分布和非正态分布的情况下,检验了用于从2×2表估计总体标准化均数差的7种不同效应量指标在偏差和抽样方差方面的表现。结果表明,有两种指标表现良好,一种基于概率单位变换,另一种基于逻辑分布。

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