Larrosa-Haro A, Coello-Ramírez P
Servicio de Gastroenterología, Hospital de Pediatría, Guadalajara, Jalisco, México.
Bol Med Hosp Infant Mex. 1992 Nov;49(11):743-9.
One hundred and sixty two patients with upper and intermediate gastrointestinal hemorrhage studied under a prospective protocol are reported. Upper endoscopy revealed lesions of the upper gastrointestinal tract in 137 patients (89%); a barium swallow performed to 92 of them failed to confirm the endoscopic diagnosis in 66 (71.7%). In 99m Tc scan suggested ectopic gastric mucosa in 9 cases; Meckel's diverticulum was confirmed by laparotomy in 7 and gastrointestinal duplication in two of them. Selective mesenteric arteriography demonstrated bleeding ileo-cecal varices in one patient. The main causes of gastrointestinal hemorrhage in the current series were duodenal ulcer (22.8%), esophageal varices (14.8%), stress ulcers (14.2%), reflux esophagitis (7.4%), aspirin-induced gastritis (6.8%), gastric ulcer (5.6%) and ectopic gastric mucosa (5.6%). These diagnosis were characteristically distributed according to pediatric age-groups. The source of bleeding could be detected in 90% of the patients studied. A clinical approach to differential diagnosis of patients with gastrointestinal bleeding is presented.
报告了162例按照前瞻性方案研究的上消化道和中消化道出血患者。上消化道内镜检查发现137例患者(89%)存在上消化道病变;对其中92例患者进行的钡餐检查未能证实内镜诊断,66例(71.7%)不符合。99m锝扫描提示9例有异位胃黏膜;7例经剖腹手术证实为梅克尔憩室,其中2例为胃肠道重复畸形。选择性肠系膜动脉造影显示1例患者存在回盲部静脉曲张出血。本系列中胃肠道出血的主要原因是十二指肠溃疡(22.8%)、食管静脉曲张(14.8%)、应激性溃疡(14.2%)、反流性食管炎(7.4%)、阿司匹林性胃炎(6.8%)、胃溃疡(5.6%)和异位胃黏膜(5.6%)。这些诊断根据儿童年龄组有特征性分布。90%的研究患者能够检测到出血来源。本文介绍了对胃肠道出血患者进行鉴别诊断的临床方法。