Phoa K H, de Baat P, de Baat C
Afdeling Mondziekten, Kaakchirurgie en Bijzondere Tandheelkunde, Erasmus Medisch Centrum, Rotterdam.
Ned Tijdschr Tandheelkd. 2003 Nov;110(11):457-9.
Scleroderma is a rare connective tissue disease of unknown origin. It is characterized by increased collagen deposition leading to fibrosis and degeneration of the skin and sometimes of internal organs. There are two main groups of scleroderma: circumscribed scleroderma and systemic sclerosis. Circumscribed scleroderma is limited to the skin and systemic sclerosis has involvement of internal organs. The main oral manifestation of scleroderma is microstoma, which is a limiting factor in oral selfcare and professional oral health care. A case report is presented of the treatment of a 15-year-old female scleroderma patient with microstoma.
硬皮病是一种病因不明的罕见结缔组织疾病。其特征是胶原蛋白沉积增加，导致皮肤纤维化和变性，有时还会累及内脏器官。硬皮病主要分为两大类：局限性硬皮病和系统性硬化症。局限性硬皮病仅累及皮肤，而系统性硬化症会累及内脏器官。硬皮病的主要口腔表现是小口畸形，这是口腔自我护理和专业口腔保健的一个限制因素。本文报告了一例15岁患有小口畸形的女性硬皮病患者的治疗情况。
