Vollmann J, Bauer A, Danker-Hopfe H, Helmchen H
Institute for History of Medicine and Medical Ethics, Friedrich-Alexander-University, Erlangen-Nuremberg, Erlangen, Germany.
Psychol Med. 2003 Nov;33(8):1463-71. doi: 10.1017/s0033291703008389.
This study investigates the competence of patients with dementia, depression and schizophrenia to make treatment decisions. The outcome of an objective test instrument is presented and compared with clinical assessment of competence by the attending physician.
The MacArthur Competence Assessment Tool-Treatment (MacCAT-T), a test instrument to assess abilities in different standards of competence, was administered to patients with diagnoses of dementia (N = 31), depression (N = 35) and schizophrenia (N = 43). Statistical significance of group differences in the MacCAT-T results were tested with the chi-square test. The concordance of the test and clinical assessment of competence by the attending physician were evaluated by Cohen's kappa coefficient.
Patients with dementia, as a group, showed significantly more often impaired performance than those with schizophrenia who were still more impaired than depressed patients. Patients were classified as impaired or not depending on the standards used. By combination of all standards substantially more patients were classified as impaired than by clinical assessment (67.7 v. 48.4% of patients with dementia, 20.0 v. 2.9% of patients with depression, 53.5 v. 18.4% of patients with schizophrenia).
Using different standards of competence the study showed substantial differences among patients with dementia, depression and schizophrenia. The high proportion of patients identified as incompetent raises several ethical questions, in particular, those referring to the selection of standards or the definition of cut-offs for incompetence. The discrepancy between clinical and formal evaluations points out the influence of the used procedure on competence judgements.
本研究调查痴呆症、抑郁症和精神分裂症患者做出治疗决策的能力。展示了一种客观测试工具的结果,并将其与主治医师对能力的临床评估进行比较。
对诊断为痴呆症(N = 31)、抑郁症(N = 35)和精神分裂症(N = 43)的患者使用麦克阿瑟治疗能力评估工具(MacCAT-T),这是一种用于评估不同能力标准下能力的测试工具。用卡方检验来检验MacCAT-T结果中组间差异的统计学显著性。通过科恩kappa系数评估该测试与主治医师对能力的临床评估之间的一致性。
作为一个群体,痴呆症患者表现出受损表现的频率明显高于精神分裂症患者,而精神分裂症患者的受损程度仍高于抑郁症患者。根据所使用的标准,患者被分类为受损或未受损。综合所有标准,被分类为受损的患者比通过临床评估的患者多得多(痴呆症患者中分别为67.7%对48.4%,抑郁症患者中为20.0%对2.9%,精神分裂症患者中为53.5%对18.4%)。
该研究使用不同的能力标准显示,痴呆症、抑郁症和精神分裂症患者之间存在显著差异。被认定为无能力的患者比例很高,这引发了几个伦理问题,特别是那些涉及标准选择或无能力临界值定义的问题。临床评估与正式评估之间的差异指出了所采用程序对能力判断的影响。