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台湾工作场所中用于结直肠癌筛查的家庭自行使用的粪便潜血试验

Home-administered fecal occult blood test for colorectal cancer screening among worksites in Taiwan.

作者信息

Hou Su-I, Chen Pai-Ho

机构信息

Department of Health Promotion and Behavior, The University of Georgia, Athens, GA 30602, USA.

出版信息

Prev Med. 2004 Jan;38(1):78-84. doi: 10.1016/j.ypmed.2003.09.031.

Abstract

BACKGROUND

This study assessed the perceived acceptance, difficulty level, and screening efficacy of home-administered fecal occult blood test (FOBT) among a Chinese population.

METHODS

Participants (age 40 and above) were recruited at various worksites in Taiwan during the summer of 2002. A single group pretest and posttest design was used.

RESULTS

The 1-month follow up rate was 81% (304/375). Screening result return rate (76%) and FOBT completion rate (74%) using the home-administered kit (HAK) were both high. Intention towards FOBT in the coming year significantly increased after the intervention (P<0.001). At pretest, participants demonstrated higher perceived acceptance and screening completion efficacy of FOBT using home-administered kit (HAK) than the traditional method (P<0.001). At posttest, the perceived difficulty of FOBT using HAK was significantly lower than the traditional stool-collecting method (P<0.001). While the acceptance of HAK remained high both before and after the intervention, the acceptance and screening efficacy towards traditional FOBT decreased significantly (P<0.001).

CONCLUSIONS

This study showed the great potential of using home-administered FOBT to promote colorectal cancer (CRC) screening among a Chinese population. Future intervention using innovative screening strategies will need to consider the participant's stage of adoption and cultural beliefs related to screening and preventive behaviors.

摘要

背景

本研究评估了中国人群对家庭自测粪便潜血试验(FOBT)的接受程度、难度水平及筛查效果。

方法

2002年夏季,在台湾的多个工作场所招募了年龄在40岁及以上的参与者。采用单组前后测设计。

结果

1个月的随访率为81%(304/375)。使用家庭自测试剂盒(HAK)的筛查结果返回率(76%)和FOBT完成率(74%)都很高。干预后,参与者在来年进行FOBT的意愿显著增加(P<0.001)。在预测试中,参与者对使用家庭自测试剂盒(HAK)进行FOBT的接受程度和筛查完成效果高于传统方法(P<0.001)。在测试后,使用HAK进行FOBT的感知难度显著低于传统粪便采集方法(P<0.001)。虽然干预前后对HAK的接受程度都很高,但对传统FOBT的接受程度和筛查效果显著下降(P<0.001)。

结论

本研究表明,使用家庭自测FOBT在促进中国人群结直肠癌(CRC)筛查方面具有巨大潜力。未来采用创新筛查策略的干预措施需要考虑参与者的采用阶段以及与筛查和预防行为相关的文化信仰。

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