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Eptifibatide-induced thrombocytopenia and circulating procoagulant platelet-derived microparticles in a patient with acute coronary syndrome.

作者信息

Morel O, Jesel L, Chauvin M, Freyssinet J M, Toti F

出版信息

J Thromb Haemost. 2003 Dec;1(12):2685-7. doi: 10.1111/j.1538-7836.2003.0543f.x.

DOI:10.1111/j.1538-7836.2003.0543f.x
PMID:14675110
Abstract
摘要

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Eptifibatide-induced thrombocytopenia and circulating procoagulant platelet-derived microparticles in a patient with acute coronary syndrome.依替巴肽诱导的急性冠状动脉综合征患者血小板减少症及循环促凝血小板衍生微粒
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Severe thrombocytopenia possibly related to readministration of eptifibatide.严重血小板减少症可能与依替巴肽再次给药有关。
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Acute thrombocytopenia after treatment with tirofiban or eptifibatide is associated with antibodies specific for ligand-occupied GPIIb/IIIa.使用替罗非班或依替巴肽治疗后出现的急性血小板减少症与针对配体占据的糖蛋白IIb/IIIa的特异性抗体有关。
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Eptifibatide-induced thrombocytopenia and thrombosis in humans require FcgammaRIIa and the integrin beta3 cytoplasmic domain.依替巴肽诱导的人类血小板减少症和血栓形成需要FcγRIIa和整合素β3胞质结构域。
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Thrombocytopenia associated with antithrombotic therapy in acute coronary syndrome.急性冠状动脉综合征中抗血栓治疗相关的血小板减少症
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Acute profound thrombocytopenia with second exposure to eptifibatide associated with a strong antibody reaction.再次使用依替巴肽后出现急性严重血小板减少症，并伴有强烈的抗体反应。
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3
Eptifibatide-induced thrombocytopenia: with thrombosis and disseminated intravascular coagulation immediately after left main coronary artery percutaneous coronary angioplasty.
依替巴肽诱导的血小板减少症：在左主干冠状动脉经皮冠状动脉介入治疗后立即出现血栓形成和弥散性血管内凝血。
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Eptifibatide-induced thrombocytopenia and thrombosis in humans require FcgammaRIIa and the integrin beta3 cytoplasmic domain.依替巴肽诱导的人类血小板减少症和血栓形成需要FcγRIIa和整合素β3胞质结构域。
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Eptifibatide-induced thrombocytopenia and thrombosis.依替巴肽诱导的血小板减少症和血栓形成。
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