Skates S, Troiano R, Knapp R C
MGH Biostatistics Center, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA.
Int J Gynecol Cancer. 2003 Sep-Oct;13(5):693-6. doi: 10.1046/j.1525-1438.2003.t01-1-13050.x.
In this case, rising longitudinal levels of CA125 were significant in the detection of peritoneal papillary serous carcinoma, and led to the indication for surgery. Rising longitudinal CA125 has been shown to be important in the detection of ovarian cancer, but little data exist as to its relevance for the detection of peritoneal papillary serous carcinoma. This rare primary tumor is usually associated with women at high risk for epithelial ovarian carcinoma, although this patient was not at high risk as she had no familial breast or ovarian cancer history.
在这种情况下,CA125纵向水平升高对腹膜乳头状浆液性癌的检测具有重要意义,并提示了手术指征。CA125纵向水平升高已被证明在卵巢癌检测中很重要,但关于其在腹膜乳头状浆液性癌检测中的相关性的数据很少。这种罕见的原发性肿瘤通常与上皮性卵巢癌高危女性相关,尽管该患者并非高危人群,因为她没有家族性乳腺癌或卵巢癌病史。