Pras Elisabeth, Wouda Jan, Willemse Pax H B, Midden Maria E, Zwart Marjolijn, de Vries Elisabeth G E, Schultz Willibrord C M Weijmar
Department of Radiation Oncology, University Hospital, Groningen, The Netherlands.
Gynecol Oncol. 2003 Dec;91(3):540-6. doi: 10.1016/j.ygyno.2003.08.002.
After pelvic radiotherapy for gynecological cancer, changes in the vaginal epithelium might influence sexual arousal and satisfaction, leading to dyspareunia and relational problems. The aim of the study was to determine the feasibility of vaginal plethysmography in order to measure physical late effects of this therapy on sexual function.
Patients treated with radiotherapy for cervical, endometrial, or ovarian cancer, who were in complete remission for over 1 year, underwent vaginal plethysmography to measure changes in vaginal vasocongestion, while watching erotic video fragments. Afterward two questionnaires, designed to measure feelings of sexual arousal during the video, and to identify sexual dysfunction, were completed. The results were compared with those of healthy women.
Patients (n = 9) and volunteers (n = 8) did not differ in baseline amplitude of plethysmography and showed comparable changes in vaginal vasocongestion during the various video fragments. The decline in amplitude during the last video fragment in the patient group did not reach significance, but the group of patients is small and heterogeneous. Addressing subjective sexual arousal during the video, patients reported less feelings of lust and desire and fewer bodily sensations while watching than the controls. Patients worried more about the sexual satisfaction of their partners than controls.
Vaginal plethysmography can be used to measure vaginal vasocongestion in patients treated with radiotherapy to the proximal vagina. In this pilot study the changes of vaginal vasocongestion during sexual arousal between patients and healthy volunteers were not different. This correlates with a comparable sexual satisfaction, although patients reported less feelings of lust.
妇科癌症盆腔放疗后，阴道上皮的变化可能会影响性唤起和性满意度，导致性交困难及关系问题。本研究旨在确定阴道体积描记法测量该疗法对性功能的远期生理影响的可行性。
接受过宫颈癌、子宫内膜癌或卵巢癌放疗且完全缓解超过1年的患者，在观看色情视频片段时接受阴道体积描记法测量阴道血管充血情况。之后完成两份问卷，一份用于测量观看视频期间的性唤起感受，另一份用于识别性功能障碍。将结果与健康女性的结果进行比较。
患者（n = 9）和志愿者（n = 8）在体积描记法的基线幅度上没有差异，并且在各个视频片段期间阴道血管充血的变化相当。患者组在最后一个视频片段期间幅度的下降未达到显著水平，但患者组规模小且异质性较大。在视频期间涉及主观的性唤起，患者报告称与对照组相比，观看时的欲望和渴望感受较少，身体感觉也较少。患者比对照组更担心伴侣的性满意度。
阴道体积描记法可用于测量接受近端阴道放疗患者的阴道血管充血情况。在这项初步研究中，患者和健康志愿者在性唤起期间阴道血管充血的变化没有差异。这与相当的性满意度相关，尽管患者报告的欲望感受较少。
