Pereira Kevin D, MacGregor Allison R, McDuffie Chad M, Mitchell Ron B
Department of Otolaryngology, The University of Texas Medical School at Houston, 6431 Fannin Street, Suite 6.112, Houston, TX 77030, USA.
Arch Otolaryngol Head Neck Surg. 2003 Dec;129(12):1268-71. doi: 10.1001/archotol.129.12.1268.
To study the indications for and outcomes of tracheostomy in a population of preterm infants.
Retrospective analysis of case records.
Two university-affiliated tertiary care children's hospitals. Patients We identified premature infants who required tracheostomies from January 1, 1997, through January 31, 2001. Information on weight, gestational age, comorbid conditions, indication for tracheostomy, and outcomes was collected. Infants were divided by birth weight into group 1 (<1000 g; n = 19 [very low birth weight]) and group 2 (> or =1000 g; n = 14). Comorbid conditions were scored and a total score was calculated for each patient.
Group 1 had a higher incidence of patent ductus arteriosus, bronchopulmonary dysplasia, intraventricular hemorrhage, and retinopathy of prematurity. The incidence of congenital or genetic defects was equal in groups 1 and 2 (11 infants [58%] and 8 infants [57%], respectively). Group 1 had a higher average number of failed extubations (5.17 vs 3.18) and a higher oxygen requirement (48.7% vs 30.3%) compared with group 2. Weight at tracheostomy was essentially equal in groups 1 and 2 (3.6 vs 3.7 kg). Subglottic stenosis and laryngotracheomalacia were equally common findings in groups 1 and 2. The average comorbidity score for group 1 was higher than that for group 2 (6.7 vs 2.8). The most common indication for tracheostomy was ventilatory dependence (n = 24 [73%]), compared with airway obstruction (n = 6 [18%]) and pulmonary toilet (n = 3 [9%]). Overall, 6 patients (18%) had a complication related to the tracheostomy.
Severity of pulmonary disease was the most significant factor associated with the need for tracheostomy in preterm infants. A tracheostomy can safely be performed in these infants with minimal morbidity.
研究早产婴儿气管切开术的适应证及结果。
病例记录回顾性分析。
两家大学附属三级护理儿童医院。患者我们确定了1997年1月1日至2001年1月31日期间需要进行气管切开术的早产儿。收集了体重、胎龄、合并症、气管切开术适应证及结果等信息。婴儿按出生体重分为1组(<1000 g;n = 19[极低出生体重])和2组(≥1000 g;n = 14)。对合并症进行评分,并计算每位患者的总分。
1组动脉导管未闭、支气管肺发育不良、脑室内出血和早产儿视网膜病变的发生率较高。1组和2组先天性或遗传性缺陷的发生率相同(分别为11例[58%]和8例[57%])。与2组相比,1组平均拔管失败次数较多(5.17比3.18),氧需求较高(48.7%比30.3%)。1组和2组气管切开时的体重基本相同(3.6比3.7 kg)。声门下狭窄和喉气管软化在1组和2组中同样常见。1组的平均合并症评分高于2组(6.7比2.8)。气管切开术最常见的适应证是通气依赖(n = 24[73%]),相比之下气道阻塞为(n = 6[18%]),肺部灌洗为(n = 3[9%])。总体而言,6例患者(18%)发生了与气管切开术相关的并发症。
肺部疾病的严重程度是与早产儿需要气管切开术相关的最显著因素。在这些婴儿中进行气管切开术可安全实施,且发病率极低。