Sardelli P, Lopez C, Loizzi M
Università degli Studi di Bari Cattedra di Chirurgia Toracica.
Ann Ital Chir. 2003 May-Jun;74(3):295-8.
A progressive and constant increase of mean life duration in the last century has determined the challenge of the treatment of lung cancer even in the elderly with good functional status. The aim of the present study is to evaluate the results obtained in the elderly, over seventy years old, who underwent pulmonary resection at our Division of Thoracic Surgery of Polyclinic of Bari from 1985 to 1995.
938 patients with NSCLC have been operated on, from January 1985 to December 1995. 189 were over seventy and 19 were over eighty years old. We have performed the following surgical procedures: 21 pneumonectomies, 108 lobectomies/bi-lobectomies, 44 wedge resections, 16 staging thoracotomies.
Post-operative complications were as follows: atelectasis 57, air leak 37, empyema 9, broncho-pleural fistula 3, arrhythmia 103, pulmonary edema 8, cardiac ischemia 3, pulmonary embolisms 1, delirium 2, hemothorax 3, exitus 5. There were 3 deaths caused by acute myocardial ischemia, one by pulmonary embolism, one by main right bronchus broncho-pleural fistula. Two and five-year overall survival were 67.1 and 37.8, respectively.
Diagnostic and therapeutical procedures for lung cancer should be different in the elderly. In our experience, main post-operative complications were cardiovascular, consequent to the entity and duration of surgical operation and intra-operative blood leaks. The elderly require a more careful post-operative monitoring to prevent this kind of complications.
上个世纪平均寿命的持续稳步增长使得即便对于功能状态良好的老年人而言,肺癌治疗也成为了一项挑战。本研究的目的是评估1985年至1995年间在我们巴里综合医院胸外科接受肺切除术的70岁以上老年人的治疗结果。
1985年1月至1995年12月期间,938例非小细胞肺癌患者接受了手术治疗。其中189例年龄超过70岁,19例年龄超过80岁。我们实施了以下手术:21例全肺切除术、108例肺叶切除/双肺叶切除术、44例楔形切除术、16例分期开胸手术。
术后并发症如下:肺不张57例、漏气37例、脓胸9例、支气管胸膜瘘3例、心律失常103例、肺水肿8例、心脏缺血3例、肺栓塞1例、谵妄2例、血胸3例、死亡5例。3例死于急性心肌缺血,1例死于肺栓塞,1例死于右主支气管支气管胸膜瘘。两年和五年总生存率分别为67.1%和37.8%。
老年人肺癌的诊断和治疗方法应有所不同。根据我们的经验,主要术后并发症是心血管方面的,这与手术的范围和持续时间以及术中出血有关。老年人需要更仔细的术后监测以预防此类并发症。