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[乌得勒支大学医学中心的全院血管筛查项目:1996年至2002年危险因素及无症状血管疾病的患病率]

[Hospital-wide vascular screening program at the University Medical Center, Utrecht: prevalence of risk factors and asymptomatic vascular disease from 1996 to 2002].

作者信息

Visseren F L, de Jaegere P P, Banga J D, Kappelle L J, Eikelboom B C, Mali W P, Algra A, van der Graaf Y

机构信息

Afd. Vasculaire Geneeskunde, Universitair Medisch Centrum Utrecht, Heidelberglaan 100, 3584 CX Utrecht.

出版信息

Ned Tijdschr Geneeskd. 2003 Nov 29;147(48):2376-82.

Abstract

OBJECTIVE

Tracing and treating cardiovascular risk factors in patients with arterial vascular disease and in patients with high risk of developing vascular diseases.

DESIGN

Descriptive.

METHOD

In September 1996 at the University Medical Center Utrecht, the Netherlands, a vascular screening and prevention programme was started for newly referred patients aged between 18 and 79 years presenting with one or more of the following: coronary artery disease, cerebrovascular disease, peripheral arterial disease, hypertension, diabetes mellitus or lipid disorders. In all patients, risk factors for developing (new) vascular diseases were assessed and non-invasive vascular diagnostics aimed at finding asymptomatic vascular disease were done.

RESULTS

Between 1 September 1996 and 31 October 2002, 3075 patients took part in the screening programme. Within the various patient groups and often despite treatment, there was a high prevalence of hypertension, smoking, dyslipidaemia, hyperhomocystemia and overweight. In patients with peripheral artery disease, carotid artery stenosis > or = 50% was detected in 17% and an aneurysm of the abdominal aorta in 5%. In patients presenting with diabetes mellitus, hypertension or lipid disorders the prevalence of asymptomatic arterial disease was 1-5%. Asymptomatic vaso-dilatory disease in particular was uncommon.

CONCLUSION

A hospital-wide vascular screening and prevention programme for a wide range of high-risk vascular patients was shown to be feasible and resulted in the detection of risk factors and asymptomatic arterial disease. It is a reliable starting point for actual risk intervention. More attention should be paid to treating existing risk factors.

摘要

目的

追踪并治疗动脉血管疾病患者以及有发生血管疾病高风险的患者的心血管危险因素。

设计

描述性研究。

方法

1996年9月,在荷兰乌得勒支大学医学中心,针对新转诊的年龄在18至79岁之间、患有以下一种或多种疾病的患者启动了一项血管筛查和预防计划:冠状动脉疾病、脑血管疾病、外周动脉疾病、高血压、糖尿病或血脂异常。对所有患者评估发生(新的)血管疾病的危险因素,并进行旨在发现无症状血管疾病的非侵入性血管诊断。

结果

1996年9月1日至2002年10月31日期间,3075名患者参加了筛查计划。在各个患者群体中,通常尽管接受了治疗,但高血压、吸烟、血脂异常、高同型半胱氨酸血症和超重的患病率仍然很高。在外周动脉疾病患者中,17%检测到颈动脉狭窄≥50%,5%检测到腹主动脉瘤。在患有糖尿病、高血压或血脂异常的患者中,无症状动脉疾病的患病率为1%-5%。特别是无症状血管舒张疾病并不常见。

结论

一项针对广泛的高风险血管患者的全院范围血管筛查和预防计划被证明是可行的,并导致了危险因素和无症状动脉疾病的发现。这是实际风险干预的可靠起点。应更加重视治疗现有的危险因素。

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