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在新加坡实施一项全国性非传染性疾病干预计划12年后,该国多民族人口主要心血管危险因素水平的变化。

Changes in the levels of major cardiovascular risk factors in the multi-ethnic population in Singapore after 12 years of a national non-communicable disease intervention programme.

作者信息

Bhalla V, Fong C W, Chew S K, Satku K

机构信息

Epidemiology and Disease Control Division, Ministry of Health, 16 College Road, Singapore 169854.

出版信息

Singapore Med J. 2006 Oct;47(10):841-50.

Abstract

INTRODUCTION

The National Healthy Lifestyle Programme, a population-wide non-communicable disease intervention programme, was started in 1992. A National Health Survey is carried out every six years to evaluate the impact of this programme on the cardiovascular risk factor profile of the resident population of Singapore.

METHODS

The 2004 National Health Survey (NHS 04) was a population-based survey carried out over a period of four months from September to December 2004. A combination of disproportionate stratified sampling and systematic sampling was used to select a representative sample (n=7,078) for the survey. The reference population comprised 2.4 million multi-racial Singaporeans aged 18-69 years. Anthropometric and blood pressure measurements were carried out on all subjects and blood samples were taken for biochemical analysis. The results were compared with those of a similar survey conducted in 1998.

RESULTS

A total of 4,084 Singapore residents took part in the survey, giving a response rate of 57.7 percent. The age-standardised prevalence of hypertension (greater than or equal to 140/90 mmHg) in Singapore residents aged 30-69 years decreased from 28.0 percent in 1998 to 24.0 percent (p-value is less than 0.001) in 2004. The prevalence of high total cholesterol (greater than or equal to 6.2 mmol/L) among those aged 18-69 years fell from 26.0 percent in 1998 to 18.1 percent (p-value is less than 0.001) in 2004. The prevalence of diabetes mellitus in residents aged 18-69 years in 2004 was 7.8 percent, compared to the 1998 level of 9.5 percent (p-value is less than 0.01). The level of obesity (body mass index is greater than or equal to 30 kg/sqm) increased slightly from 6.2 percent in 1998 to 6.8 percent (p-value equals 0.1627). The prevalence of daily smoking decreased from 15.0 percent in 1998 to 12.5 percent in 2004 (p-value is less than 0.001), while that of regular exercise increased from 17.0 percent to 25.0 percent (p-value is less than 0.001). Ethnic differences in the prevalence of diabetes mellitus, hypertension, hypercholesterolaemia, and exercise were observed.

CONCLUSION

The NHS 04 results suggest that the National Healthy Lifestyle Programme significantly decreased daily smoking, high blood cholesterol and hypertension, and increased regular exercise over 1998 levels. The results also suggest that the programme stabilised the prevalence of obesity and diabetes mellitus.

摘要

引言

全国健康生活方式计划是一项针对全体人群的非传染性疾病干预计划,于1992年启动。每六年进行一次全国健康调查,以评估该计划对新加坡常住人口心血管危险因素状况的影响。

方法

2004年全国健康调查(NHS 04)是一项基于人群的调查,于2004年9月至12月进行了四个月。采用不成比例分层抽样和系统抽样相结合的方法,选取了一个具有代表性的样本(n = 7,078)进行调查。参考人群包括240万年龄在18 - 69岁的多民族新加坡人。对所有受试者进行了人体测量和血压测量,并采集血样进行生化分析。将结果与1998年进行的类似调查结果进行了比较。

结果

共有4,084名新加坡居民参与了调查,应答率为57.7%。30 - 69岁新加坡居民中高血压(大于或等于140/90 mmHg)的年龄标准化患病率从1998年的28.0%降至2004年的24.0%(p值小于0.001)。18 - 69岁人群中高总胆固醇(大于或等于6.2 mmol/L)的患病率从1998年的26.0%降至2004年的18.1%(p值小于0.001)。2004年18 - 69岁居民中糖尿病的患病率为7.8%,而1998年为9.5%(p值小于0.01)。肥胖水平(体重指数大于或等于30 kg/sqm)从1998年的6.2%略有上升至6.8%(p值等于0.1627)。每日吸烟的患病率从1998年的15.0%降至2004年的12.5%(p值小于0.001),而经常锻炼的患病率从17.0%升至25.0%(p值小于0.001)。观察到糖尿病、高血压、高胆固醇血症和锻炼患病率存在种族差异。

结论

NHS 04的结果表明,全国健康生活方式计划显著降低了每日吸烟率、高血胆固醇和高血压,并使经常锻炼的比例高于1998年的水平。结果还表明,该计划稳定了肥胖和糖尿病的患病率。

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