大鼠睡眠期间慢波活动的变化。

Variations in slow wave activity during sleep in the rat.

作者信息

Rosenberg R S, Bergmann B M, Rechtschaffen A

机构信息

Sleep Laboratory, University of Chicago, Chicago, IL 60637, USA.

出版信息

Physiol Behav. 1976 Dec;17(6):931-8. doi: 10.1016/0031-9384(76)90011-1.

DOI:10.1016/0031-9384(76)90011-1

PMID:14677585

Abstract

Scoring of human electroencephalogram (EEG) recordings usually includes subdivisions of non-rapid eye movement (NREM) sleep based on amount of slow wave activity. This procedure has revealed relationships between slow wave activity and many other variables. In animals, however, few experimenters have described variations in slow wave activity within NREM sleep. The present study quantifies, by filtering and integration techniques, variations in amount of slow wave activity during NREM sleep in the rat. Slow wave activity was found to be greatest at the start of the light period; the diurnal variation of slow wave activity within NREM sleep was correlated with variations in amount of NREM sleep. An amplitude criterion was used to define NREM sleep, but overall EEG amplitude during NREM sleep did not show the same diurnal variation as slow wave activity. The results indicate the value of measuring variations in slow wave amplitude during NREM sleep in animals in addition to overall EEG amplitude.

摘要

人类脑电图（EEG）记录的评分通常包括根据慢波活动量对非快速眼动（NREM）睡眠进行细分。这一过程揭示了慢波活动与许多其他变量之间的关系。然而，在动物研究中，很少有实验者描述NREM睡眠期间慢波活动的变化。本研究通过滤波和积分技术对大鼠NREM睡眠期间慢波活动量的变化进行了量化。结果发现，慢波活动在光照期开始时最强；NREM睡眠期间慢波活动的昼夜变化与NREM睡眠量的变化相关。使用振幅标准来定义NREM睡眠，但NREM睡眠期间的总体脑电图振幅并未表现出与慢波活动相同的昼夜变化。结果表明，除了总体脑电图振幅外，测量动物NREM睡眠期间慢波振幅的变化也具有重要价值。