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组织胞浆菌病与获得性免疫缺陷综合征:预后因素研究

Histoplasmosis and acquired immunodeficiency syndrome: a study of prognostic factors.

作者信息

Couppié Pierre, Sobesky Milko, Aznar Christine, Bichat Saravane, Clyti Emmanuel, Bissuel François, El Guedj Myriam, Alvarez Fernand, Demar Magali, Louvel Dominique, Pradinaud Roger, Carme Bernard

机构信息

Service de Dermatologie-Vénéréologie, Centre Hospitalier de Cayenne, French Guiana.

出版信息

Clin Infect Dis. 2004 Jan 1;38(1):134-8. doi: 10.1086/379770. Epub 2003 Dec 4.

Abstract

We aimed to identify prognostic factors for AIDS-associated disseminated histoplasmosis. In a multivariate analysis, we found that dyspnea, a platelet count of <100,000 platelets/mm3, and lactate dehydrogenase levels of >2 times the upper limit of the normal range were significantly independently associated with the death of the patient during the first 30 days of antifungal treatment.

摘要

我们旨在确定艾滋病相关播散性组织胞浆菌病的预后因素。在多变量分析中,我们发现呼吸困难、血小板计数<100,000/立方毫米以及乳酸脱氢酶水平>正常范围上限的2倍与患者在抗真菌治疗的前30天内死亡显著独立相关。

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