Guetersloh Stephen B, Borak Thomas B, Taddei Phillip J, Zeitlin Cary, Heilbronn Lawrence, Miller Jack, Murakami Takeshi, Iwata Yoshiyuki
Department of Radiological Health Sciences, Colorado State University, Fort Collins, Colorado 80523, USA.
Radiat Res. 2004 Jan;161(1):64-71. doi: 10.1667/rr3101.
The response of a tissue-equivalent proportional counter (TEPC) to different ions having a similar linear energy transfer (LET) has been studied. Three ions, 14N, 20Ne and 28Si, were investigated using the HIMAC accelerator at the National Institute of Radiological Sciences at Chiba, Japan. The calculated linear energy transfer (LET( infinity )) of all ions was 44 +/- 2 keV/microm at the sensitive volume of the TEPC. A particle spectrometer was used to record the charge and position of each incident beam particle. This enabled reconstruction of the location of the track as it passed though the TEPC and ensured that the particle survived without fragmentation. The spectrum of energy deposition events in the TEPC could be evaluated as a function of trajectory through the TEPC. The data indicated that there are many events from particles that did not pass through the sensitive volume. The fraction of these events increased as the energy of the particle increased due to changes in the maximum energy of the delta rays. Even though the LET of the incident particles was nearly identical, the frequency-averaged lineal energy, y(F), as well as the dose-averaged lineal energy, y(D), varied with the velocity of the incident particle. However, both values were within 15% of LET in all cases.
研究了组织等效正比计数器(TEPC)对具有相似线能量转移(LET)的不同离子的响应。使用位于日本千叶的国立放射科学研究所的HIMAC加速器研究了三种离子,即14N、20Ne和28Si。在TEPC的灵敏体积处,所有离子的计算线能量转移(LET(∞))为44±2 keV/μm。使用粒子谱仪记录每个入射束粒子的电荷和位置。这使得能够重建粒子穿过TEPC时的轨迹位置,并确保粒子在不发生碎裂的情况下存活。TEPC中能量沉积事件的谱可以作为粒子穿过TEPC的轨迹的函数进行评估。数据表明,有许多事件来自未穿过灵敏体积的粒子。由于δ射线最大能量的变化,这些事件的比例随着粒子能量的增加而增加。尽管入射粒子的LET几乎相同,但频率平均线能量y(F)以及剂量平均线能量y(D)随入射粒子的速度而变化。然而,在所有情况下,这两个值都在LET的15%以内。