Taddei Phillip J, Zhao Zhongxiang, Borak Thomas B
Department of Radiation Physics, Unit 94, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA.
Radiat Meas. 2008 Oct;43(9-10):1498-1505. doi: 10.1016/j.radmeas.2008.09.003.
Monte Carlo simulations of heavy ion interactions using the Geant4 toolkit were compared with measurements of energy deposition in a spherical tissue-equivalent proportional counter (TEPC). A spherical cavity with a physical diameter of 12.7 mm was filled with propane-based tissue-equivalent gas surrounded by a wall of A-150 tissue-equivalent plastic that was 2.54 mm to thick. Measurements and Monte Carlo simulations were used to record the energy deposition and the trajectory of the incident particle on an event-by-event basis for ions ranging in atomic number from 2 ((4)He) to 26 ((56)Fe) and in energy from 200 MeV/nucleon to 1000 MeV/nucleon. In the simulations, tracking of secondary electrons was terminated when the range of an electron was below a specified threshold. The effects of range cuts for electrons at 0.5 μm, 1 μm, 10 μm, and 100 μm were evaluated. To simulate an energy deposition influenced by large numbers of low energy electrons with large transverse momentum, it was necessary to track electrons down to range cuts of 10 μm or less. The Geant4 simulated data closely matched the measured data acquired using a TEPC for incident particles traversing the center of the detector as well as near the gas-wall interface. Values of frequency mean lineal energy and dose mean lineal energy were within 8% of the measured data. The production of secondary particles in the aluminum vacuum chamber had no effect on the response of the TEPC for (56)Fe at 1000 MeV/nucleon. The results of this study confirm that Geant4 can simulate patterns of energy deposition for existing microdosimeters and is valuable for improving the design of a new generation of detectors used for space dosimetry and for characterizing particle beams used in hadron radiotherapy.
利用Geant4工具包对重离子相互作用进行了蒙特卡罗模拟,并与球形组织等效正比计数器(TEPC)中能量沉积的测量结果进行了比较。一个物理直径为12.7毫米的球形腔室充满了丙烷基组织等效气体,周围是一层厚度为2.54毫米的A - 150组织等效塑料壁。测量和蒙特卡罗模拟用于逐个事件记录原子序数从2((4)He)到26((56)Fe)、能量从200 MeV/核子到1000 MeV/核子的离子的能量沉积和入射粒子的轨迹。在模拟中,当电子的射程低于指定阈值时,二次电子的追踪终止。评估了电子在0.5μm、1μm、10μm和100μm处射程截断的影响。为了模拟受大量具有大横向动量的低能电子影响的能量沉积,有必要将电子追踪到10μm或更小的射程截断。对于穿过探测器中心以及靠近气壁界面的入射粒子,Geant4模拟数据与使用TEPC获取的测量数据紧密匹配。频率平均线能量和剂量平均线能量的值在测量数据的8%以内。铝真空室中二次粒子的产生对1000 MeV/核子的(56)Fe的TEPC响应没有影响。本研究结果证实,Geant4可以模拟现有微剂量计的能量沉积模式,对于改进用于空间剂量测定的新一代探测器的设计以及表征强子放射治疗中使用的粒子束具有重要价值。