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[乙肝疫苗接种无效病例——个人观察]

[Cases of ineffective anti-hepatitis B vaccination--own observations].

作者信息

Kepa Lucjan, Oczko-Grzesik Barbara, Sobala-Szczygieł Barbara, Stolarz Wojciech, Wilczek Krzysztof, Mossor Krystyna, Warakomska Iwona, Dziambor Andrzej P

机构信息

Oddział Chorób Zakaźnych Slaskiej Akademii Medycznej w Bytomiu.

出版信息

Przegl Epidemiol. 2003;57(3):491-7.

PMID:14682168
Abstract

Between 1999-2001 there were 6 patients with acute hepatitis B, previously vaccinated according to the recommended schedule of anti-hepatitis B immunization for adults, hospitalized in the Department of Infectious Diseases (Bytom, Silesian University Medical School). The study presents epidemiological and clinical analysis of these cases. Special attention is paid to possibility of immune response failure in spite of anti-hepatitis B vaccination. It is emphasized, that efficiency of active hepatitis B prophylaxis should be verified by estimation of serum anti-HBs antibodies, especially in patients with planned surgery.

摘要

1999年至2001年间,有6例急性乙型肝炎患者入住西里西亚大学医学院传染病科(比托姆),这些患者此前已按照成人乙型肝炎免疫接种推荐程序进行了疫苗接种。本研究对这些病例进行了流行病学和临床分析。特别关注了尽管接种了乙型肝炎疫苗但仍可能出现免疫反应失败的情况。强调对于计划进行手术的患者,应通过检测血清抗-HBs抗体来验证乙型肝炎主动预防的效果。

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