Milde F K, Hart L K, Zehr P S
College of Nursing, University of Iowa Hospitals and Clinics, University of Iowa, Iowa City 52242.
Diabetes Care. 1992 Nov;15(11):1459-63. doi: 10.2337/diacare.15.11.1459.
To comprehensively assess and compare pancreas/kidney transplant recipients' quality of life.
This quasi-experimental comparative study of 31 successful and 13 failed pancreas transplant recipients collected data from persons who had received pancreas and kidney transplants > or = 6 mo prior at a university tertiary care center. Physical and social function, symptoms, mental state, and sense of well-being of the recipients were assessed.
Groups did not differ significantly regarding age, gender, marital status, onset or length of diabetes, comorbidity, type of prior dialysis, current kidney function, length of time since transplant, physical activity, symptom burden, emotional state, feelings of well-being, and present quality of life and health. A significant time by group interaction occurred for quality of life (P = 0.0013) and health (P = 0.0001). The successful group indicated that both quality of life and health were significantly better than in the past, and continued improvement was expected. The unsuccessful group did not have this perception. Members of the failed group were significantly more satisfied with their social support. The unsuccessful group's major concerns related to diabetes, not immunosuppression.
Recipients of successful pancreas transplants perceived their improvement in health and quality of life to be significantly greater than the unsuccessful recipients.
全面评估和比较胰肾联合移植受者的生活质量。
这项对31例成功的和13例失败的胰肾联合移植受者进行的准实验性比较研究,收集了在一所大学三级医疗中心接受胰肾联合移植≥6个月的患者的数据。评估了受者的身体和社会功能、症状、精神状态及幸福感。
两组在年龄、性别、婚姻状况、糖尿病起病情况或病程、合并症、既往透析类型、当前肾功能、移植后时间长度、身体活动、症状负担、情绪状态、幸福感以及当前生活质量和健康状况方面无显著差异。在生活质量(P = 0.0013)和健康状况(P = 0.0001)方面,组间与时间存在显著交互作用。成功组表示生活质量和健康状况均显著优于过去,且预计会持续改善。失败组则没有这种认知。失败组的成员对其社会支持的满意度显著更高。失败组主要担忧的是糖尿病,而非免疫抑制。
成功接受胰腺移植的受者认为其健康状况和生活质量的改善显著大于未成功的受者。