Phenolic thiazoles as novel orally-active neuroprotective agents.
作者信息
Harnett Jeremiah J, Roubert Veronique, Dolo Christine, Charnet Christelle, Spinnewyn Brigitte, Cornet Sylvie, Rolland Alain, Marin Jean-Gregoire, Bigg Dennis, Chabrier Pierre-E
机构信息
Department of Medicinal Chemistry, Ipsen Research Laboratories, Institute Henri Beaufour, 5 Avenue du Canada, 91966 Les Ulis Cedex, France.
出版信息
Bioorg Med Chem Lett. 2004 Jan 5;14(1):157-60. doi: 10.1016/j.bmcl.2003.09.077.
PMID:14684319
Abstract
Novel phenolic thiazoles compounds were prepared which demonstrated potent antioxidant activity and potent in vivo neuroprotection in mitochondrial toxin models and also possess good oral bioavailability.
摘要
Zotero 插件