Watanabe H, Ishigooka M, Kubota Y, Iijima Y, Sasagawa I, Nakada T
Department of Urology, Yamagata University School of Medicine, Japan.
Eur Urol. 1992;22(3):247-9. doi: 10.1159/000474764.
We measured penile blood flow during physiological erection using the Xenon-133 clearance method in order to diagnose the exact cause of impotence. In 16 patients, in whom complete erection was obtained after visual sexual stimulation, the mean penile blood flow during erection was apparently higher than that in the flaccid state. On the contrary, in 6 patients whose reaction to visual stimulation was poor, penile blood flow did not change before and after stimulation. We considered that increased arterial flow was indispensable, but complete venous outlet obstruction was not necessary to produce a rigid erection. In addition, in the flaccid state the mean penile blood flow in the poor response group was apparently higher than that in the response group. This means that some patients who fail to obtain sufficient erection after visual sexual stimulation have increased venous outflow from the corpus cavernosum in the flaccid state. Based on these findings, the main cause of erectile dysfunction in such cases is probably attributed to disorders of the venous outlet system in the cavernous body.
我们采用氙-133清除法测量生理性勃起过程中的阴茎血流，以诊断阳痿的确切病因。16例患者在视觉性刺激后能完全勃起，勃起时阴茎平均血流明显高于疲软状态。相反，6例对视觉刺激反应较差的患者，刺激前后阴茎血流无变化。我们认为增加动脉血流是必不可少的，但要产生坚硬勃起并不一定需要完全的静脉出口阻塞。此外，在疲软状态下，反应较差组的阴茎平均血流明显高于反应组。这意味着一些在视觉性刺激后未能获得充分勃起的患者，在疲软状态下海绵体静脉流出增加。基于这些发现，此类病例勃起功能障碍的主要原因可能归因于海绵体静脉出口系统紊乱。
