Kamat Ashish M
Department of Urology, University of Texas, MD Anderson Cancer Center, Houston 77030, USA.
Expert Rev Anticancer Ther. 2003 Dec;3(6):799-808. doi: 10.1586/14737140.3.6.799.
The American Cancer Society estimates that 57,400 new cases of bladder cancer will be diagnosed in the USA in 2003 and that approximately 70% of these cases will be superficial bladder tumors. Due to the high risk of recurrence, patients with superficial bladder cancer represent an ideal group for chemoprevention. Intravesical chemotherapy or immunotherapy is often administered in an attempt to prevent tumor recurrence in high-risk patients, although it is not without toxicity. A large body of evidence links diet and nutrition with bladder cancer. This review summarizes the efficacy of natural and synthetic agents that have purported chemopreventive activity.
美国癌症协会估计，2003年美国将有57400例新发膀胱癌病例被诊断出来，其中约70%将是浅表性膀胱肿瘤。由于复发风险高，浅表性膀胱癌患者是化学预防的理想群体。膀胱内化疗或免疫疗法常被用于试图预防高危患者的肿瘤复发，尽管它并非没有毒性。大量证据将饮食和营养与膀胱癌联系起来。本综述总结了具有化学预防活性的天然和合成药物的疗效。
