肠易激综合征中的直肠功能与排便习惯
Rectal function and bowel habit in irritable bowel syndrome.
作者信息
Distrutti Eleonora, Salvioli Beatrice, Azpiroz Fernando, Malagelada Juan R
机构信息
Digestive System Research Unit, University Hospital Vall d'Hebron, Autonomous University of Barcelona, Barcelona, Spain.
出版信息
Am J Gastroenterol. 2004 Jan;99(1):131-7. doi: 10.1046/j.1572-0241.2003.04012.x.
OBJECTIVES
Rectal compliance may influence rectal perception, but their functional implications remain incompletely understood. Our aim was to determine whether rectal function is related to bowel habit in the irritable bowel syndrome.
METHODS
The responses to fixed tension rectal distension applied by means of a tensostat were compared among constipation-predominant (n = 9), diarrhea-predominant (n = 7), alternating habit (n = 11) irritable syndrome subgroups, and healthy controls (n = 15).
RESULTS
Overall, patients had normal rectal compliance and increased perception, but compliance was lower in diarrhea-predominant as compared to constipation-predominant patients (6.7 +/- 0.7 ml/mmHg vs. 9.9 +/- 0.7 ml/mmHg, respectively; p < 0.05) and perception was higher (39 +/- 6 g vs. 64 +/- 9 g tolerance, respectively; p < 0.05).
CONCLUSION
Distinctive tensosensitivity and compliance characterize rectal function in irritable bowel syndrome subgroups with different bowel habit.
目的
直肠顺应性可能影响直肠感知，但它们的功能意义仍未完全明了。我们的目的是确定在肠易激综合征中直肠功能是否与排便习惯有关。
方法
比较了以张力调节器施加固定张力直肠扩张时，便秘型（n = 9）、腹泻型（n = 7）、交替型（n = 11）肠易激综合征亚组以及健康对照者（n = 15）的反应。
结果
总体而言，患者直肠顺应性正常但感知增强，不过腹泻型患者的顺应性低于便秘型患者（分别为6.7±0.7 ml/mmHg和9.9±0.7 ml/mmHg；p<0.05），而感知更高（耐受量分别为39±6 g和64±9 g；p<0.05）。
结论
具有不同排便习惯的肠易激综合征亚组的直肠功能具有独特的张力敏感性和顺应性特征。
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