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How long should patients be followed after molar pregnancy? Analysis of serum hCG follow-up data.

作者信息

Batorfi Jozsef, Vegh Gyorgy, Szepesi Janos, Szigetvari Ivan, Doszpod Jozsef, Fulop Vilmos

机构信息

Department of Obstetrics and Gynecology, National Health Center, 35 Szabolcs Street, Budapest 1135, Hungary.

出版信息

Eur J Obstet Gynecol Reprod Biol. 2004 Jan 15;112(1):95-7. doi: 10.1016/s0301-2115(03)00274-4.

Abstract

OBJECTIVE

We analyzed human chorionic gonadotropin (hCG) follow-up data of patients with molar pregnancy. Women often do not complete recommended post-disease screening. Our purpose was to determine if continuing follow up of uncomplicated molar cases beyond attaining undetectable hCG levels is necessary for detecting relapse of gestational trophoblastic disease.

STUDY DESIGN

One hundred fifty patients treated at Hungarian National Health Center were analyzed. Those who developed persistent disease before hCG had become undetectable were excluded from further analysis (n=24; 16%).

RESULTS

Among 126 uncomplicated cases, 72 patients (57%) completed follow up, and 54 (43%) discontinued their protocol before it had been completed. Of 120 patients who achieved at least one undetectable hCG level, none had any evidence of relapse.

CONCLUSION

In uncomplicated hydatidiform mole, our analysis indicates that once undetectable serum hCG levels are attained, relapse is unlikely. Although further monthly checks are advisable, the likelihood of recurrence appears very low.

摘要

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