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葡萄胎妊娠中的短暂甲状腺毒症

Transient Thyrotoxicosis in Molar Pregnancy.

作者信息

Virmani Samarth, Srinivas Sujatha B, Bhat Rama, Rao Raghavendra, Kudva Ranjini

机构信息

Medical Student, Department of Medicine, Kasturba Medical College, Manipal University, Manipal, Karnataka, India.

Assistant Professor, Department of Obstetrics and Gynaecology, Kasturba Medical College, Manipal University, Manipal, Karnataka, India.

出版信息

J Clin Diagn Res. 2017 Jul;11(7):QD01-QD02. doi: 10.7860/JCDR/2017/28561.10133. Epub 2017 Jul 1.

Abstract

Molar pregnancy is one of the components of a broader spectrum of diseases known as Gestational Trophoblastic Disease (GTD), presenting with amenorrhoea and irregular bleeding which may be rarely associated with passage of vesicles per vagina. However, it can rarely be associated with hyperthyroidism, which may be associated with clinical features of hyperthyroidism. The following is a report of a 20-year-old woman who presented with amenorrhea followed by irregular bleeding per vagina, thyromegaly and abnormal levels of thyroid hormones. Transvaginal ultrasound revealed features consistent with molar pregnancy. A suction evacuation was done following which serum levels of β-hCG reduced and the levels of thyroid hormones also reduced. On follow up, six weeks later, β-hCG and thyroid hormones were within normal limits. The case and relevant literature are presented here.

摘要

葡萄胎是妊娠滋养细胞疾病(GTD)这一更广谱疾病的组成部分之一,表现为闭经和不规则阴道出血,极少数情况下可能伴有阴道排出水泡状物。然而,它很少与甲状腺功能亢进相关,而甲状腺功能亢进可能伴有甲状腺功能亢进的临床特征。以下是一名20岁女性的病例报告,该患者先是闭经,随后出现阴道不规则出血、甲状腺肿大以及甲状腺激素水平异常。经阴道超声检查显示的特征符合葡萄胎。进行了刮宫术,之后血清β - hCG水平下降,甲状腺激素水平也下降。六周后的随访显示,β - hCG和甲状腺激素水平均在正常范围内。本文展示了该病例及相关文献。

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Transient Thyrotoxicosis in Molar Pregnancy.葡萄胎妊娠中的短暂甲状腺毒症
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本文引用的文献

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Clinical practice. Molar pregnancy.临床实践。葡萄胎妊娠。
N Engl J Med. 2009 Apr 16;360(16):1639-45. doi: 10.1056/NEJMcp0900696.
5
Gestational trophoblastic disease.妊娠滋养细胞疾病
Clin Obstet Gynecol. 2007 Mar;50(1):112-22. doi: 10.1097/GRF.0b013e31802f17fc.
7
How long should patients be followed after molar pregnancy? Analysis of serum hCG follow-up data.
Eur J Obstet Gynecol Reprod Biol. 2004 Jan 15;112(1):95-7. doi: 10.1016/s0301-2115(03)00274-4.
8
Perioperative management of the thyrotoxic patient.甲状腺毒症患者的围手术期管理。
Endocrinol Metab Clin North Am. 2003 Jun;32(2):519-34. doi: 10.1016/s0889-8529(03)00010-0.
10
Gestational trophoblastic disease.妊娠滋养细胞疾病
J Obstet Gynaecol Can. 2002 May;24(5):434-46.

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