Shprintzen R J, Singer L
Int Anesthesiol Clin. 1992 Fall;30(4):109-14.
Both the etiology of Robin sequence and the mechanisms of upper airway obstruction are heterogeneous. As a result, generalizations about the care of newborns with the combination of micrognathia, cleft palate, and airway obstruction cannot be made. Management of the airway obstruction should be based on the results of direct endoscopic observation of the site of obstruction and not on the presumptive diagnosis of glossoptosis. It should not be assumed that "catch-up growth" of the mandible will occur and lead to spontaneous resolution of either the airway obstruction or the micrognathia. The presentation of the child with Pierre Robin sequence should not be the end of the diagnostic search, but rather the beginning.
罗宾序列征的病因及上呼吸道梗阻的机制均具有异质性。因此，无法对患有小颌畸形、腭裂和气道梗阻的新生儿护理进行一概而论。气道梗阻的处理应基于对梗阻部位的直接内镜观察结果，而非舌后坠的推测性诊断。不应假定下颌骨会出现“追赶生长”并导致气道梗阻或小颌畸形自行缓解。患有皮埃尔·罗宾序列征患儿的临床表现不应是诊断探索的终点，而应是起点。
