Meira Z M, Barros M V, Capanema F D, Castilho S R, Vitarelli A M, Mota C C
Departmento de Pediatria, UFMG.
J Pediatr (Rio J). 1996 Sep-Oct;72(5):324-8. doi: 10.2223/jped.636.
To determine the prevalence of innocent murmur among adolescents, and to evaluate the clinical features in comparison with echocardiogram (two-dimensional, M-mode, Doppler, and color-Doppler) in the assessment of heart murmurs.
The study was carried out from March to December, 1992, and involved high school students coming from families of the medium and low-medium social classes. Considering the total of 1400 students registered in a public school, 536 adolescents aging from 10 to 20 years were admitted in this study. Twenty seven students with heart murmur were submitted to Echocardiography in order to find any cardiac lesions.
Among 536 adolescents, 171 (32%) had some kind of heart murmur. On the basis of the clinical diagnosis, 160 (29.9%) patients were classified as having innocent murmur and 11 (2.1%) as having "pathologic murmur". Out of 27 students submitted to echocardiography, 20 of them with clinical diagnosis of innocent murmur showed normal results. Among seven students with clinical diagnosis of "pathologic murmur", the echocardiography recognized cardiac lesions in two (small ventricular septal defect and rheumatic heart disease: combined mitral incompetence and stenosis, and aortic incompetence).
From the data obtained, the prevalence of innocent murmur among adolescents was 29.9% on the basis of clinical diagnosis. It is suggested that careful clinical examination by physicians skilled in cardiac examination is the recommended method for the diagnosis of innocent murmur (sensitivity of 100% and specificity of 80%).
确定青少年中无害性杂音的患病率,并在评估心脏杂音时,与超声心动图(二维、M型、多普勒和彩色多普勒)比较,评估其临床特征。
该研究于1992年3月至12月进行,纳入来自社会中低阶层家庭的高中生。考虑到一所公立学校登记的1400名学生总数,本研究纳入了536名年龄在10至20岁的青少年。27名有心脏杂音的学生接受了超声心动图检查,以查找任何心脏病变。
在536名青少年中,171名(32%)有某种心脏杂音。根据临床诊断,160名(29.9%)患者被归类为有无害性杂音,11名(2.1%)为有“病理性杂音”。在接受超声心动图检查的27名学生中,20名临床诊断为无害性杂音的学生结果正常。在7名临床诊断为“病理性杂音”的学生中,超声心动图识别出2名有心脏病变(小型室间隔缺损和风湿性心脏病:二尖瓣关闭不全合并狭窄,以及主动脉瓣关闭不全)。
根据获得的数据,基于临床诊断,青少年中无害性杂音的患病率为29.9%。建议由精通心脏检查的医生进行仔细的临床检查,这是诊断无害性杂音的推荐方法(敏感性为100%,特异性为80%)。